Applications | Tested Dilution | Publications |
---|---|---|
Western Blot (WB) |
1:1,000 | - |
Immunohistochemistry (IHC) |
1:125-1:500 | - |
Product Specifications | |
---|---|
Species Reactivity |
Human |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
Between 1300 and C-term |
Conjugate |
Unconjugated |
Form |
liquid |
Concentration |
0.50 mg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
TBS with 0.1% BSA |
Contains |
0.09% sodium azide |
Storage conditions |
4° C |
The recommended shelf life for this product is 1 year from date of receipt.
Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
The DNA mismatch repair MSH2/MSH6 heterodimer is responsible for the detection of DNA damage, and may promote apoptosis in normal cells, thus protecting mammals from ultraviolet-induced malignant transformation and hence the prevention of skin cancer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: DNA mismatch repair protein Msh6; G/T mismatch-binding protein; GTBP; hMSH6; mutS (E. coli) homolog 6; MutS alpha 160kDa subunit; MutS protein homolog 6; MutS-alpha 160 kDa subunit; MutS-alpha 160kDa subunit; p160; Sperm associated protein; sperm-associated protein
Gene Aliases: GTBP; GTMBP; HNPCC5; HSAP; MSH6; p160
UniProt ID: (Human) P52701
Entrez Gene ID: (Human) 2956
Molecular Function:
DNA metabolism protein
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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