Musashi-1 belongs to the Musashi family of RNA-binding proteins which play a role in cell fate determination, and maintenance of stem-cell state. Musashi family proteins are also involved in post transcriptional gene regulation. The gene encodes a protein with two conserved tandem RNA recognition motifs with highly conserved RNP (ribonucleoprotein) motifs. In mammals, Musashi-1 is expressed in fetal kidney, brain, liver and lung, and in adult brain and pancreas. In humans, the gene is located on chromosome 12.
Protein Aliases: Musashi homolog 1(Drosophila); musashi RNA-binding protein 1; Musashi-1; musashi1; RNA-binding protein Musashi homolog 1
Gene Aliases: m-Msi-1; MSI1; Msi1h; Musahi1
Molecular Function: RNA splicing factor