Musashi-1 belongs to the Musashi family of RNA-binding proteins which play a role in cell fate determination, and maintenance of stem-cell state. Musashi family proteins are also involved in post transcriptional gene regulation. The gene encodes a protein with two conserved tandem RNA recognition motifs with highly conserved RNP (ribonucleoprotein) motifs. In mammals, Musashi-1 is expressed in fetal kidney, brain, liver and lung, and in adult brain and pancreas. In humans, the gene is located on chromosome 12.
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Protein Aliases: musashi RNA-binding protein 1; Musashi-1; musashi1; RNA-binding protein Musashi homolog 1
Gene Aliases: MSI1
UniProt ID: (Human) O43347
Entrez Gene ID: (Human) 4440