MA5-15839 targets MSX1 in WB applications and shows reactivity with Human samples.
The MA5-15839 immunogen is purified recombinant fragment of human MSX1 expressed in E. Coli.
MA5-15839 detects MSX1 which has a predicted molecular weight of approximately 31kDa.
MSX1 is a member of the muscle segment homeobox gene family. It functions as a transcriptional repressor during embryogenesis through interactions with components of the core transcription complex and other homeoproteins. MSX1 may also have roles in limb-pattern formation, craniofacial development, particularly odontogenesis, and tumor growth inhibition. Mutations in the gene, which was once known as homeobox 7, have been associated with nonsyndromic cleft lip with or without cleft palate 5, Witkop syndrome, Wolf-Hirschom syndrome, and autosomoal dominant hypodontia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: homeobox 7; Homeobox protein Hox-7; Homeobox protein MSX-1; msh homeo box 1; Msh homeobox 1-like protein; msh homeobox homolog 1
Gene Aliases: ECTD3; HOX7; HYD1; MSX1; STHAG1
UniProt ID: (Human) P28360
Entrez Gene ID: (Human) 4487