MA5-15839 targets MSX1 in WB applications and shows reactivity with Human samples.
The MA5-15839 immunogen is purified recombinant fragment of human MSX1 expressed in E. Coli.
MA5-15839 detects MSX1 which has a predicted molecular weight of approximately 31kDa.
Drosophila,muscle segment (msh) homolog 1,homeo domain encoding gene,inhibiting MYOD1 expression,highly expressed in dental mesenchyme during critical bud stage,involved in epithelial-mesenchymal signaling in many organs,and in the pathogenesis of cleft lip and palate,interacting with MSX2 in mouse limb bud patterning .This gene encodes a member of the muscle segment homeobox gene family. The encoded protein functions as a transcriptional repressor during embryogenesis through interactions with components of the core transcription complex and other homeoproteins. It may also have roles in limb-pattern formation, craniofacial development, particularly odontogenesis, and tumor growth inhibition.Tissue specificity: Expressed in the developing nail bed mesenchyme.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: homeobox 7; Homeobox protein Hox-7; Homeobox protein MSX-1; HOX7, HYD1, STHAG1, homeobox 7; msh homeo box 1; Msh homeobox 1-like protein; msh homeobox homolog 1
Gene Aliases: ECTD3; HOX7; HYD1; MSX1; STHAG1
UniProt ID: (Human) P28360
Entrez Gene ID: (Human) 4487