Applications | Tested Dilution | Publications |
---|---|---|
Western Blot (WB) |
1-5 µg/mL | - |
Immunohistochemistry (Paraffin) (IHC (P)) |
1.5 µg/mL | - |
ELISA (ELISA) |
10 µg/mL | - |
Product Specifications | |
---|---|
Species Reactivity |
Human |
Host/Isotype |
Mouse / IgG2a, kappa |
Class |
Monoclonal |
Type |
Antibody |
Clone |
1F6 |
Immunogen |
MSX2 (NP_002440, 101 a.a. approximately 201 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
See Label |
Purification |
Affinity chromatography |
Storage buffer |
PBS, pH 7.4 |
Contains |
no preservative |
Storage conditions |
-20° C, Avoid Freeze/Thaw Cycles |
Sequence of this protein is as follows: TASVKSENSE DGAAWMQEPG RYSPPPRHMS PTTCTLRKHK TNRKPRTPFT TSQLLALERK FRQKQYLSIA ERAEFSSSLN LTETQVKIWF QNRRAKAKRL *
Msx2 is a transcriptional repressor whose normal activity may establish a balance between survival and apoptosis of neural crest-derived cells required for proper craniofacial morphogenesis. This protein may also have a role in promoting cell growth under certain conditions and may be an important target for the RAS signaling pathways. Mutations in the Msx2 gene are associated with parietal foramina 1 and craniosynostosis type 2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Homeobox protein Hox-8; Homeobox protein MSX-2; msh homeo box 2; msh homeobox homolog 2
Gene Aliases: CRS2; FPP; HOX8; MSH; MSX2; PFM; PFM1
UniProt ID: (Human) P35548
Entrez Gene ID: (Human) 4488
Molecular Function:
homeodomain transcription factor
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