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MT-ND5 Polyclonal Antibody detects endogenous levels of MT-ND5 protein.
A small number of complex I subunits are the products of mitochondrial genes (subunits 1-7), while the remainder are nuclear encoded and imported from the cytoplasm. NADH dehydrogenase subunit 5 (ND5) is most likely a component of the hydrophobic protein fragment of Complex I. Mutations in the gene encoding for ND5 are implicated in Mitochondrial neurogastrointestinal encephalomyopathy, an autosomal recessive multisystem disorder that results in dramatically elevated levels of circulating thymidine and deoxyuridine.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: NADH Dehydrogenase 5; NADH dehydrogenase subunit 5; NADH-ubiquinone oxidoreductase chain 5
Gene Aliases: MT-ND5; MTND5; NADH5; ND5
UniProt ID: (Human) P03915
Entrez Gene ID: (Human) 4540
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