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Product Details
CL647-67561
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Mouse
/ IgG2b
Class
Monoclonal
Type
Antibody
Clone
1A8B2
Immunogen
Recombinant protein
Conjugate
Excitation/Emission Max
654/674 nm
Form
Liquid
Purification
Protein A
Storage buffer
PBS with 50% glycerol, 0.5% BSA
Contains
0.05% ProClin 300
Storage conditions
-20° C, store in dark
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: LSIPYPGCEF FKEYKDRDYM AEGLIFNWKQ DYVDAPLSIP DFLTHSLNID WSQYQCWDLV QQTQNYLKLL LSLVNSDDDS GLLVHCISGW DRTPLFISLL RLSLWADGLI HTSLKPTEIL YLTVAYDWFL FGHMLVDRLS KGEEIFFFCF NFLKHITSEE FSALKTQRRK SLPARDGGFT LEDICMLRRK DRGSTTSLGS DFSLVMESSP GATGSFTYEA VELVPAGAPT QAAWRKSHSS SPQSVLWNRP QPSEDRLPSQ QGLAEARSSS SSSSNHSDNF FRMGSSPLEV PKPRLAALSD RETRLQEVRS AFLAAYSSTV GLRAVAPSPS GAIGGLLEQF ARGVGLRSIS SNAL
Target Information
This gene encodes a myotubularin-related protein. The encoded protein is a phosphoinositide phosphatase that specifically dephosphorylates phosphatidylinositol 3,5-biphosphate and phosphatidylinositol 3-phosphate. Mutations in this gene are correlated with autosomal dominant centronuclear myopathy. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 18.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: egg-derived tyrosine phosphatase homolog; HCV NS5A-transactivated protein 4 splice variant A-binding protein 1; hJumpy; jumpy; mJumpy; Myotubularin-related protein 14; NS5ATP4ABP1
Gene Aliases: 1110061O04Rik; AW553738; C3orf29; C76151; MTMR14; RGD1304842
UniProt ID: (Human) Q8NCE2, (Mouse) Q8VEL2
Entrez Gene ID: (Human) 64419, (Mouse) 97287, (Rat) 312634
phosphatidylinositol-3-phosphatase activity
protein serine/threonine phosphatase activity
protein tyrosine phosphatase activity
protein binding
phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity
protein tyrosine/serine/threonine phosphatase activity
protein tyrosine/threonine phosphatase activity
JUN kinase phosphatase activity
phosphohistidine phosphatase activity
inositol bisphosphate phosphatase activity
hydrolase activity
phosphatase activity
MAP kinase tyrosine/serine/threonine phosphatase activity
inositol-1,3,4-trisphosphate 4-phosphatase activity
NADP phosphatase activity
transmembrane receptor protein phosphatase activity
inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase activity
inositol-1,4,5,6-tetrakisphosphate 6-phosphatase activity
inositol-4,5-bisphosphate 5-phosphatase activity
5-amino-6-(5-phosphoribitylamino)uracil phosphatase activity
phosphatidylinositol-4-phosphate phosphatase activity
phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity
inositol phosphate phosphatase activity
inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity
inositol-3,4-bisphosphate 4-phosphatase activity
inositol-1,3,4-trisphosphate 1-phosphatase activity
inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity
inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity
phosphatidylinositol-1,4,5-trisphosphate 5-phosphatase activity
IDP phosphatase activity
hydrolase
phosphatase
metabolite interconversion enzyme
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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