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|Tested species reactivity||Human|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Purified, full length, native human protein from ovarian carcinoma.|
|Storage buffer||TBS, pH 7.5|
|Contains||0.05% sodium azide|
|Storage Conditions||4° C, do not freeze|
|Tested Applications||Dilution *|
|ELISA (ELISA)||Assay Dependent|
|Immunohistochemistry (Paraffin) (IHC (P))||Assay Dependent|
|Western Blot (WB)||Assay Dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
MA1-24603 detects MUC16 from human samples.
MA1-24603 has been successfully used in ELISA, immunohistochemistry (paraffin), and Western blot procedures.
The MA1-24603 immunogen is purified, full length, native human protein from ovarian carcinoma.
CA125/MUC16 antigen is a serum marker that is used routinely in gynecologic practice to monitor patients with ovarian cancer. It is a mullerian duct differentiation antigen that is overexpressed in epithelial ovarian cancer cells and secreted into the blood, although its expression is not entirely confined to ovarian cancer. Most biochemical studies have concluded that CA125/MUC16 is a high molecular mass glycoprotein, although estimates of its size range from 200 to 2000 kDa with smaller.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
CA125; CA125 ovarian cancer antigen; FLJ14303; ovarian cancer-related tumor marker CA125; ovarian carcinoma antigen CA125