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NeoBiotechnologies
Applications | Tested Dilution | Publications |
---|---|---|
Immunohistochemistry (Paraffin) (IHC (P)) |
1-2 µg/mL | - |
Product Specifications | |
---|---|
Species Reactivity |
Human |
Host/Isotype |
Rabbit / IgG |
Class |
Recombinant Monoclonal |
Type |
Antibody |
Clone |
OCA125, 2349R |
Immunogen |
Purified human MUC16 protein |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
200 µg/mL |
Purification |
Protein A |
Storage buffer |
PBS, pH 7.4, with 0.05% BSA |
Contains |
0.05% sodium azide |
Storage conditions |
4° C |
Immunohistochemistry (PFA fixed): incubate antibody for 30 min RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95 degrees C followed by cooling at RT for 20 minutes.
CA 125 determinant is present on a high molecular weight, mucin like glycoprotein of high molecular weight. CA 125 has been found on frozen sections of amnion and derivatives of coelomic and mullerian epithelium, including pleura, pericardium and peritoneum. In adult tissues, epithelial cells of fallopian tube, endometrium and endocervix; pancreas, colon, gall bladder, stomach, kidney, apocrine sweat gland and mammary gland. It is also found in mesothelial cell lining of pleura, pericardium and peritoneum. It is found in ovarian tumors of serous, endometrioid or clear cell types and adenocarcinomas of mullerian type.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CA-125; ca-ovarian; CA125 ovarian cancer antigen; FLJ14303; MUC-16; Mucin-16; Ovarian cancer-related tumor marker CA125; Ovarian carcinoma antigen CA125
Gene Aliases: CA125; MUC16
UniProt ID: (Human) Q8WXI7
Entrez Gene ID: (Human) 94025
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