|Tested species reactivity||Human|
|Published species reactivity||Human, Not Applicable|
|Host / Isotype||Mouse / IgG1|
|Immunogen||This information is considered to be commercially sensitive.|
|Storage buffer||PBS, pH 7.4|
|Contains||0.09% sodium azide|
|Storage Conditions||4°C or -20°C if preferred|
|Tested Applications||Dilution *|
|Flow Cytometry (Flow)||Assay-Dependent|
|Immunohistochemistry (Frozen) (IHC (F))||Assay Dependent|
|Immunohistochemistry (Paraffin) (IHC (P))||Assay Dependent|
|Western Blot (WB)||Assay Dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Immunohistochemistry (IHC)||See 5 publications below|
MA1-25020 detects MUC2 from human samples.
MA1-25020 has been successfully used in immunohistochemistry (paraffin), and Western blot procedures.
The MA1-25020 immunogen is considered to be commercially sensitive.
This gene encodes a member of the mucin protein family. Mucins are high molecular weight glycoproteins produced by many epithelial tissues. The protein encoded by this gene is secreted and forms an insoluble mucous barrier that protects the gut lumen. The protein polymerizes into a gel of which 80% is composed of oligosaccharide side chains by weight. The protein features a central domain containing tandem repeats rich in threonine and proline that varies between 50 and 115 copies in different individuals. Alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Microsatellite Instability of Gastric and Colorectal Cancers as a Predictor of Synchronous Gastric or Colorectal Neoplasms.
MA1-25020 was used in immunohistochemistry to utilize a predictor for synchronous colorectal or gastric neoplasms by presence of microsatellite instability of colorectal and gastric cancers
|Kim YB,Lee SY,Kim JH,Sung IK,Park HS,Shim CS,Han HS||Gut and liver (10:220)||2016|
Early Gastric Cancer-Like Advanced Gastric Cancer versus Advanced Gastric Cancer-Like Early Gastric Cancer.
MA1-25020 was used in immunohistochemistry to study endoscopic differences between early gastric cancer that resembles advanced gastric cancer and advanced gastric cancer that resembles early gastric cancer
|Park HS,Lee SY,Hong SN,Kim JH,Sung IK,Park HS,Shim CS,Jin CJ||Clinical endoscopy (46:155)||2013|
Change of mucosal color in early gastric cancer.
MA1-25020 was used in immunohistochemistry to report on the diagnostic value of mucosal color changes in early gastric cancer
|Lee HH,Lee SY,Yoon HY,Hong SN,Kim JH,Sung IK,Park HS,Shim CS,Han HS||Journal of digestive diseases (13:510)||2012|
MUC5AC, cytokeratin 20 and HER2 expression and K-RAS mutations within mucinogenic growth in congenital pulmonary airway malformations.
MA1-25020 was used in immunohistochemistry to investigate the changes of gene expression in congenital pulmonary airway malformations
|Rossi G,Gasser B,Sartori G,Migaldi M,Costantini M,Mengoli MC,Piccioli S,Cavazza A,Rivasi F||Histopathology (60:1133)||2012|
Unclassified mucin phenotype of gastric adenocarcinoma exhibits the highest invasiveness.
MA1-25020 was used in immunohistochemistry to investigate phenotypic mucin expression in human gastric adenocarcinoma
|Han HS,Lee SY,Lee KY,Hong SN,Kim JH,Sung IK,Park HS,Jin CJ,Min YI||Journal of gastroenterology and hepatology (24:658)||2009|