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|Tested species reactivity||Human|
|Host / Isotype||Goat / IgG|
|Immunogen||Synthetic peptide sequence (DYKSSLIQDGNPM) corresponding to the N-terminus amino acids of TRIM63|
|Purification||Antigen affinity chromatography|
|Storage buffer||TBS, pH 7.3, with 0.5% BSA|
|Contains||0.02% sodium azide|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Immunohistochemistry (IHC)||Assay Dependent|
|Immunohistochemistry (Paraffin) (IHC (P))||Assay-Dependent|
|Western Blot (WB)||0.1 µg/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
This antibody is predicted to react with bovine and canine based on sequence homology.
This gene encodes a member of the RING zinc finger protein family found in striated muscle and iris. The product of this gene is localized to the Z-line and M-line lattices of myofibrils, where titin's N-terminal and C-terminal regions respectively bind to the sarcomere. In vitro binding studies have shown that this protein also binds directly to titin near the region of titin containing kinase activity. Another member of this protein family binds to microtubules. Since these family members can form heterodimers, this suggests that these proteins may serve as a link between titin kinase and microtubule-dependent signal pathways in muscle.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
FLJ32380; IRF; iris ring finger protein; MURF-1; MURF1; MURF2; muscle specific ring finger protein 1; muscle specific ring finger protein 2; muscle-specific RING finger protein 1; ring finger protein 28; RNF28; SMRZ; striated muscle RING zinc finger protein; TRIM63; tripartite motif containing 63, E3 ubiquitin protein ligase; tripartite motif-containing 63; tripartite motif-containing protein 63
IRF; MURF1; MURF2; RNF28; SMRZ; TRIM63