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Invitrogen
MX1 Recombinant Rabbit Monoclonal Antibody (HL2051)
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
MA5-47268
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Dog,
Cat,
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
HL2051
Immunogen
Recombinant fragment of human MX1
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
PBS
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Store as concentrated solution.
Centrifuge briefly prior to opening vial.
Target Information
This gene encodes a guanosine triphosphate (GTP)-metabolizing protein that participates in the cellular antiviral response. The encoded protein is induced by type I and type II interferons and antagonizes the replication process of several different RNA and DNA viruses. There is a related gene located adjacent to this gene on chromosome 21, and there are multiple pseudogenes located in a cluster on chromosome 4. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: GTP-binding protein Mx1; interferon-induced GTP-binding protein Mx1; interferon-induced protein p78; interferon-inducible protein p78; interferon-regulated resistance GTP-binding protein MxA; Mx1; Mx1 isoform 1; Mx1 isoform 2; myxoma resistance protein 1; myxovirus (influenza virus) resistance 1; myxovirus (influenza virus) resistance 1, interferon-inducible protein p78; myxovirus (influenza) resistance 1 polypeptide; myxovirus resistance protein 1; p78 protein; unnamed protein product
Gene Aliases: IFI-78K; IFI78; lncMX1-215; MX; Mx-1; MxA
UniProt ID: (Dog) Q9N0Y3, (Human) P20591, (Mouse) P09922
Entrez Gene ID: (Dog) 403745, (Human) 4599, (Mouse) 17857
apoptotic process
defense response
signal transduction
response to virus
synaptic vesicle budding from presynaptic endocytic zone membrane
response to type I interferon
negative regulation of viral genome replication
innate immune response
defense response to virus
interleukin-27-mediated signaling pathway
antiviral innate immune response
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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