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MYBPC3 Recombinant Rabbit Monoclonal Antibody (19H1L3)
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FIGURE: 1 / 2
MYBPC3 Antibody (703574) in WB
Western blot was performed using Anti-MYBPC3 Recombinant Rabbit Monoclonal Antibody (Product # 703574) and a 150 kDa band corresponding to MYBPC3 was observed across the cell lines and tissues tested. Whole cell extracts (30 µg lysate) of iPSC (Lane 1), iPSC differentiated into cardiomyocytes (Lane 2) and tissue extracts of Mouse Heart (Lane 3), Mouse Skeletal Muscle (Lane 4), Rat Heart (Lane 5) and Rat Skeletal Muscle (Lane 6) were electrophoresed using Novex® NuPAGE® 4-12 % Bis-Tris gel (Product # NP0322BOX). Resolved proteins were then ... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
703574
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Mouse
Host/Isotype
Rabbit
/ IgG
Expression System
Expi293
Class
Recombinant Monoclonal
Type
Antibody
Clone
19H1L3
Immunogen
Protein corresponding to human MYBPC3 [aa1-aa115]
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.5 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
PBS, pH 7.2-7.4
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
Product Specific Information
This antibody is predicted to react with Bovine.
Target Information
Myosin binding protein C, cardiac-type (MYBPC3) is a thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments. It modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role. Mutations affecting the gene can result in cardiomyopathy - familial hypertrophic 4, cardiomyopathy - dilated 1MM, or left ventricular non-compaction 10.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: cardiac C-protein; cardiac MyBP-C; DKFZp779E1762; myosin binding protein C, cardiac; sarcomeric protein; unnamed protein product
Gene Aliases: CMD1MM; CMH4; cMyBP-C; FHC; LVNC10; MYBP-C
UniProt ID: (Human) Q14896, (Rat) P56741
Entrez Gene ID: (Human) 4607, (Rat) 295929, (Mouse) 17868
heart morphogenesis
regulation of striated muscle contraction
regulation of muscle filament sliding
sarcomere organization
ventricular cardiac muscle tissue morphogenesis
cardiac muscle contraction
regulation of cardiac muscle cell contraction
regulation of heart rate
regulation of heart contraction
myosin filament assembly
muscle contraction
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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