MA5-11971 targets Myosin Smooth Muscle Heavy Chain in IF and IHC (P) applications and shows reactivity with Bovine and Human samples.
The MA5-11971 immunogen is crude human uterus extract.
SM-MHC is a cytoplasmic structural protein, which is a major component of the contractile apparatus in smooth muscle cells. Expression of smooth muscle myosin is developmently regulated, appearing early in smooth muscle development, and is specific for smooth muscle development. Two isoforms of smooth muscle myosin heavy chain have been identified, designated MHC-1 and MHC-2.
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Protein Aliases: heavy polypeptide 11; myosin; myosin heavy chain; Myosin heavy chain 11; myosin heavy chain 11, smooth muscle; myosin heavy chain SMA; Myosin heavy chain, smooth muscle isoform; myosin, heavy chain 11, smooth muscle; myosin, heavy polypeptide 11, smooth muscle; Myosin-11; SMMHC; smooth muscle; smooth muscle isoform
Gene Aliases: AAT4; AV071570; BOS_22758; FAA4; KIAA0866; MYH11; SM1; SM2; SMHC; SMMHC
UniProt ID: (Human) P35749