Positive Control: HeLa, MYH9-transfected 293T
Predicted Reactivity: Mouse (100%), Rat (100%), Dog (100%)
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.
MYH9 encodes a myosin IIA heavy chain that contains an IQ domain and a myosin head-like domain. The protein is involved in several important functions, including cytokinesis, cell motility and maintenance of cell shape. Defects in MYH9 are the cause of non-syndromic sensorineural deafness autosomal dominant type 17, Epstein syndrome, Alport syndrome with macrothrombocytopenia, Sebastian syndrome, Fechtner syndrome and macrothrombocytopenia with progressive sensorineural deafness.
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Protein Aliases: BDPLT6; Cellular myosin heavy chain, type A; DFNA17; EPSTS; FTNS; heavy chain 9; MHA; MYH9; myosin; Myosin heavy chain 9; Myosin heavy chain, non-muscle IIa; Myosin-9; NMHC-II A; NMMHC II-a; NMMHC IIA; NMMHC-A; NMMHCA; non-muscle; non-muscle myosin heavy chain 9; Non-muscle myosin heavy chain A; Non-muscle myosin heavy chain IIa; non-muscle myosin heavy polypeptide 9; nonmuscle myosin heavy chain II-A
Gene Aliases: BDPLT6; DFNA17; EPSTS; FTNS; MHA; MYH9; NMHC-II-A; NMMHC-IIA; NMMHCA
UniProt ID: (Human) P35579
Entrez Gene ID: (Human) 4627