MA5-15694 targets MYOD1 in WB applications and shows reactivity with Human samples.
The MA5-15694 immunogen is purified recombinant fragment of human MYOD1 expressed in E. Coli.
MA5-15694 detects MYOD1 which has a predicted molecular weight of approximately 34kDa.
This gene encodes a nuclear protein that belongs to the basic helix-loop-helix family of transcription factors and the myogenic factors subfamily. It regulates muscle cell differentiation by inducing cell cycle arrest, a prerequisite for myogenic initiation. The protein is also involved in muscle regeneration. It activates its own transcription which may stabilize commitment to myogenesis.
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Protein Aliases: bHLHc1; Class C basic helix-loop-helix protein 1; Myf-3; MYF3; Myoblast determination protein 1; MYOD; MYOD1; Myogenic factor 3
Gene Aliases: BHLHC1; MYF3; MYOD; MYOD1; PUM
UniProt ID: (Human) P15172
Entrez Gene ID: (Human) 4654