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|Tested species reactivity||Human|
|Published species reactivity||Human|
|Host / Isotype||Mouse / IgG2b|
|Immunogen||Purified recombinant fragment of human MYST1 expressed in E. Coli.|
|Contains||0.03% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Immunofluorescence (IF)||1/200 - 1/1000|
|Immunohistochemistry (IHC)||1/200 - 1/1000|
|Western Blot (WB)||1/500 - 1/2000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Immunocytochemistry (ICC)||See 1 publications below|
MA5-15345 targets MYST1 in IF, IHC, and WB applications and shows reactivity with Human samples.
The MA5-15345 immunogen is purified recombinant fragment of human MYST1 expressed in E. Coli.
MA5-15345 detects MYST1 which has a predicted molecular weight of approximately 53kDa.
The MYST family of histone acetyltransferases, which includes MYST1, is named for the founding members MOZ , yeast YBF2 and SAS2, and TIP60 . All members of this family contain a MYST region of about 240 amino acids with a canonical acetyl-CoA-binding site and a C2HC-type zinc finger motif. Most MYST proteins also have a chromodomain involved in protein-protein interactions and targeting transcriptional regulators to chromatin .
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Modulation of chromatin remodelling induced by the freshwater cyanotoxin cylindrospermopsin in human intestinal caco-2 cells.
MA5-15345 was used in immunocytochemistry to study the effect of the freshwater cyanotoxin cylindrospermopsin on chromatin remodelling
|Huguet A,Hatton A,Villot R,Quenault H,Blanchard Y,Fessard V||PloS one (9:null)||2014|
FLJ14040; histone acetyltransferase MYST1; hMOF; K(lysine) acetyltransferase 8; KAT8; MOF; MOZ, YBF2/SAS3, SAS2 and TIP60 protein 1; MYST histone acetyltransferase 1; MYST-1; MYST1; ortholog of Drosophila males absent on the first (MOF); probable histone acetyltransferase MYST1
hMOF; KAT8; MOF; MYST1; PP7073; ZC2HC8