MA5-15345 targets MYST1 in IF, IHC, and WB applications and shows reactivity with Human samples.
The MA5-15345 immunogen is purified recombinant fragment of human MYST1 expressed in E. Coli.
MA5-15345 detects MYST1 which has a predicted molecular weight of approximately 53kDa.
The MYST family of histone acetyltransferases, which includes MYST1, is named for the founding members MOZ , yeast YBF2 and SAS2, and TIP60 . All members of this family contain a MYST region of about 240 amino acids with a canonical acetyl-CoA-binding site and a C2HC-type zinc finger motif. Most MYST proteins also have a chromodomain involved in protein-protein interactions and targeting transcriptional regulators to chromatin .
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Protein Aliases: FLJ14040; Histone acetyltransferase KAT8; histone acetyltransferase MYST1; hMOF; K(lysine) acetyltransferase 8; KAT8; Lysine acetyltransferase 8; MOF; MOZ, YBF2/SAS3, SAS2 and TIP60 protein 1; MYST histone acetyltransferase 1; MYST-1; MYST1; ortholog of Drosophila males absent on the first (MOF); probable histone acetyltransferase MYST1
Gene Aliases: hMOF; KAT8; MOF; MYST1; PP7073; ZC2HC8
UniProt ID: (Human) Q9H7Z6
Entrez Gene ID: (Human) 84148