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Positive control: Mamma carcinoma (normal mamma shows up lower expression of the protein), skin sweat glands.
Reactivity: Human and other primates (no reactivity in chicken, cat, rabbit, rat, sheep and goat).
Mammaglobin is a gene that is expressed almost exclusively in the normal breast epithelium and human breast cancer. It is a member of the secretoglobin gene family and forms a heterodimer with lipophilin B. It has been suggested that mammaglobin may be a useful marker for breast cancer clinical research. Studies investigating the detection of mRNA by RT PCR from circulating carcinoma cells in the peripheral blood of breast cancer patients have shown that mammaglobin is a highly specific marker and correlates with several prognostic factors, such as lymph node involvement.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: HGNC:7050; mammaglobin 1; mammaglobin A; Mammaglobin-1; Mammaglobin-A; MGC71974; prostatein; Secretoglobin family 2A member 2; secretoglobin, family 2A, member 2
Gene Aliases: MGB1; SCGB2A2; UGB2
UniProt ID: (Human) Q13296
Entrez Gene ID: (Human) 4250
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