|Tested species reactivity||Human|
|Published species reactivity||Human|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Recombinant full-length protein|
|Storage buffer||PBS, pH 7.4, with 0.2% BSA|
|Contains||0.09% sodium azide|
|Storage Conditions||4° C|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||1:100|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Immunohistochemistry (IHC)||See 1 publications below|
MA5-12638 targets Mammaglobin in IHC (P) applications and shows reactivity with Human samples.
The MA5-12638 immunogen is recombinant full-length protein.
Mammaglobin, a member of the uteroglobin family, is a 10kDa glycoprotein. Mammaglobin mRNA expression is breast tissue specific. It is overexpressed in human breast cancer. The use of Mammaglobin RT-PCR has been demonstrated to detect disseminated breast cancer. In a study to evaluate the frequency and specificity of mammaglobin, 80% of all primary and metastatic breast tumors tested were immunopositive irrespective of tumor grade, while mammaglobin mRNA was detected in 60% of the peripheral stem cell collections from breast cancer patients.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
A systematic analysis of commonly used antibodies in cancer diagnostics.
MA5-12638 was used in immunohistochemistry to perform a systematic study of the diagnostic power of a range of antibodies commonly used in the diagnosis of cancer
|Gremel G,Bergman J,Djureinovic D,Edqvist PH,Maindad V,Bharambe BM,Khan WA,Navani S,Elebro J,Jirström K,Hellberg D,Uhlén M,Micke P,Pontén F||Histopathology (64:293)||2014|