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|Tested species reactivity||Human|
|Published species reactivity||Human|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Recombinant protein corresponding to the membrane-bound form of the mesothelin molecule|
|Storage buffer||tissue culture supernatant|
|Contains||0.09% sodium azide|
|Storage Conditions||4° C|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||1:5-1:10|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Immunohistochemistry (IHC)||See 3 publications below|
MA5-11918 targets Mesothelin in IHC (P) applications and shows reactivity with Human samples.
The MA5-11918 immunogen is recombinant protein corresponding to the membrane-bound form of the mesothelin molecule.
Mesothelin is a glycocylphosphotidylianositol-linked cell-surface glycoprotein, that is present on the surface of normal mesothelium and is overexpressed in many patients with epithelial ovarian cancer and malignant mesotheliomas.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
The angiogenesis inhibitor thrombospondin-1 inhibits acute cutaneous hypersensitivity reactions.
MA5-11918 was used in immunohistochemistry to study the effect of thrombospondin-1 on acute cutaneous hypersensitivity reactions
|Velasco P,Huegel R,Brasch J,Schröder JM,Weichenthal M,Stockfleth E,Schwarz T,Lawler J,Detmar M,Lange-Asschenfeldt B||The Journal of investigative dermatology (129:2022)||2009|
Primary localized malignant biphasic mesothelioma of the liver in a patient with asbestosis.
MA5-11918 was used in immunohistochemistry to report a clinical case of primary localized malignant biphasic mesothelioma of the liver associated with asbestosis
|Sasaki M,Araki I,Yasui T,Kinoshita M,Itatsu K,Nojima T,Nakanuma Y||World journal of gastroenterology (15:615)||2009|
Biomarkers in Diagnosis of pancreatic carcinoma in fine-needle aspirates.
MA5-11918 was used in immunohistochemistry to identify diagnostic markers for pancreatic carcinoma
|Jhala N,Jhala D,Vickers SM,Eltoum I,Batra SK,Manne U,Eloubeidi M,Jones JJ,Grizzle WE||American journal of clinical pathology (126:572)||2006|
CAK1 antigen; megakaryocyte potentiating factor; pre-pro-megakaryocyte-potentiating factor; soluble MPF mesothelin related protein
MPF; MSLN; SMRP