Note: You clicked on an external link, which has been disabled in order to keep your shopping session open.
|Tested species reactivity||Human, Primate|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Spleen lymphocytes from mice fused with OVCAR-3, an ovarian tumor cell line derived from poorly differentiated adenocarcinoma of the ovary.|
|Storage buffer||PBS with 1% BSA|
|Contains||0.1% sodium azide|
|Storage Conditions||4° C|
|Tested Applications||Dilution *|
|Immunocytochemistry (ICC)||Assay Dependent|
|Immunohistochemistry (Frozen) (IHC (F))||1:40|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
MA1-26527 detects Mesothelin from human and Cynomolgus monkey samples.
MA1-26527 has been successfully used in immunohistochemistry (frozen) procedures.
The MA1-26527 immunogen is spleen lymphocytes from mice fused with OVCAR-3, an ovarian tumor cell line derived from poorly differentiated adenocarcinoma of the ovary.
An antibody that reacts with ovarian cancers and mesotheliomas was used to isolate a cell surface antigen named mesothelin. Although the function of mesothelin is unknown, it may play a role in cellular adhesion and is present on mesothelium, mesotheliomas, and ovarian cancers. This gene encodes a preproprotein that is cleaved into two products, megakaryocyte potentiating factor and mesothelin. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
CAK1; CAK1 antigen; megakaryocyte potentiating factor; MPF; pre-pro-megakaryocyte-potentiating factor; SMR; soluble MPF mesothelin related protein
MPF; MSLN; SMRP