|Tested species reactivity||Mouse, Bovine, Human|
|Published species reactivity||Mouse, Human, Not Applicable|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Fusion protein between the catalytic domain of human Methionine Aminopeptidase-2 (MetAP-2) and GST|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7.4|
|Contains||0.1% sodium azide|
|Tested Applications||Dilution *|
|ELISA (ELISA)||Assay Dependent|
|Western Blot (WB)||Assay Dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
The ADP-ribosylation factor (Arf) family are highly conserved members of the Ras superfamily of regulatory GTP-binding proteins. Arf proteins participate in routing of intracellular proteins to and within the Golgi complex. Cellular functions include maintenance of organelle integrity, coat protein assembly, as an activator of phospholipase D. The Arf family is divided functionally into the Arf and the Arf-like (Arl) proteins. The ARF proteins are categorized as class I (ARF1, ARF2,and ARF3), class II (ARF4 and ARF5) and class III (ARF6) and members of each class share a common gene organization.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
|Mouse||Not Cited||24-hour oscillation of mouse methionine aminopeptidase2, a regulator of tumor progression, is regulated by clock gene proteins.||Nakagawa H,Koyanagi S,Takiguchi T,Kuramoto Y,Soeda S,Shimeno H,Higuchi S,Ohdo S||Cancer research (64:8328)||2004|
|Human||Not Cited||A methionine aminopeptidase-2 inhibitor, PPI-2458, for the treatment of rheumatoid arthritis.||Bernier SG,Lazarus DD,Clark E,Doyle B,Labenski MT,Thompson CD,Westlin WF,Hannig G||Proceedings of the National Academy of Sciences of the United States of America (101:10768)||2004|
|Not Applicable||Not Cited||
Characterization of recombinant microsporidian methionine aminopeptidase type 2.
71-7200 was used in western blot to characterize recombinant microsporidian methionine aminopeptidase type 2
|Weiss LM,Zhou GC,Zhang H||The Journal of eukaryotic microbiology (50 Suppl:597)||2004|
|Human||Not Cited||Methionine aminopeptidase-2 regulates human mesothelioma cell survival: role of Bcl-2 expression and telomerase activity.||Catalano A,Romano M,Robuffo I,Strizzi L,Procopio A||The American journal of pathology (159:721)||2001|
|Human||Not Cited||Protacs: chimeric molecules that target proteins to the Skp1-Cullin-F box complex for ubiquitination and degradation.||Sakamoto KM,Kim KB,Kumagai A,Mercurio F,Crews CM,Deshaies RJ||Proceedings of the National Academy of Sciences of the United States of America (98:8554)||2001|
||Methionine aminopeptidase-2 regulates human mesothelioma cell survival: role of Bcl-2 expression and telomerase activity.||Catalano A,Romano M,Robuffo I,Strizzi L,Procopio A||The American journal of pathology (159:721)||2001|