Purity: >95% by SDS-Page
Endotoxin Concentration: ≤1 EUs/µg
Protein Length: 163 aa.
Biological Activity: <10 ng/mL
Molecular Weight: 18.6 kDa
Animal Origin Free: Yes
Reconstitute with 0.1 mg/mL sterile water
FLT3LG (Fms Related Tyrosine Kinase 3 Ligand) is a Protein Coding gene. Diseases associated with FLT3LG include Aplastic Anemia and Brain Cancer. Among its related pathways are Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers and Ras signaling pathway. Gene Ontology (GO) annotations related to this gene include protein homodimerization activity and cytokine activity. Dendritic cells (DCs) provide the key link between innate and adaptive immunity by recognizing pathogens and priming pathogen-specific immune responses. FLT3LG controls the development of DCs and is particularly important for plasmacytoid DCs and CD8-positive classical DCs and their CD103-positive tissue counterparts.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Flt 3 ligand; Flt3 L; Flt3 ligand; Fms-related tyrosine kinase 3 ligand; H-FLT-3-L; M-FLT-3-L; SL cytokine
Gene Aliases: Flt3l; Flt3lg; Ly72L
UniProt ID: (Mouse) P49772
Entrez Gene ID: (Mouse) 14256