Recombinant mouse IL-15 is a non-glycosylated protein, containing 163 amino acids, with a molecular weight of 18.6 kDa. Purity is typically greater than 98% and endotoxin level less than 1 EU/ug.
The expected biological activity (ED50) is determined by the dose-dependent induction of CTLL-2 cell proliferation and is typically less than 5 ng/mL. The specific activity of this protein is 2x10^5 units/mg.
Reconstitute using sterile water at 0.1 mg/mL and centrifuge prior to opening vial. Gently pipet solution down the sides of the vial. DO NOT VORTEX sample. Store reconstituted material at -20°C and add 0.1% BSA for additional stability.
Amino acid sequence: MTPDCYFSHS PISSNFKVKF RELTDHLLKD YPVTVAVNLQ DEKHCKALWS LFLAQRWIEQ LKTVAGSKMQ TLLEDVNTEI HFVTSCTFQP LPECLRFVQT NISHLLKDTC TQLLALKPCI GKACQNFSRC LEVQCQPDSS TLLPPRSPIA LEATELPEPR PRQ.
FMS-related Tyrosine Kinase 3 Ligand (FLT-3 Ligand) is a growth factor important for the proliferation of hematopoietic cells. FLT-3 Ligand binds to, and transmits signals through, the receptor tyrosine kinase known as FMS-like Tyrosine Kinase-3 (FLT-3). FLT-3 Ligand promotes long-term expansion and differentiation of human pro-B cells in the presence of IL-7 or in combination of IL-7 and IL-3. Human FLT-3 Ligand can stimulate the proliferation of cells expressing murine FLT-3 receptors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Flt3 ligand; Fms-related tyrosine kinase 3 ligand; M-FLT-3-L; SL cytokine
Gene Aliases: Flt3l; Flt3lg; Ly72L
UniProt ID: (Mouse) P49772
Entrez Gene ID: (Mouse) 14256