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|Tested species reactivity||Mouse|
|Published species reactivity||Not Applicable|
|Host / Isotype||Goat / IgG|
|Conjugate||Alexa Fluor® 594|
|Storage buffer||PBS, pH 7.5|
|Contains||5mM sodium azide|
|Storage Conditions||4° C, store in dark|
|Cross Adsorption||Against mouse IgM, mouse IgA, pooled human sera, purified human paraproteins and mouse isotypes IgG1, IgG2a and IgG3 prior to conjugation|
|Antibody Form||Whole Antibody|
|Tested Applications||Dilution *|
|Flow Cytometry (Flow)||1-10 µg/mL|
|Immunocytochemistry (ICC)||1-10 µg/ml|
|Immunofluorescence (IF)||1-10 µg/mL|
|Immunohistochemistry (IHC)||1-10 µg/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
Anti-Mouse secondary antibodies are affinity-purified antibodies with well-characterized specificity for mouse immunoglobulins and are useful in the detection, sorting or purification of its specified target. Secondary antibodies offer increased versatility enabling users to use many detection systems (e.g. HRP, AP, fluorescence). They can also provide greater sensitivity through signal amplification as multiple secondary antibodies can bind to a single primary antibody. Most commonly, secondary antibodies are generated by immunizing the host animal with a pooled population of immunoglobulins from the target species and can be further purified and modified (i.e. immunoaffinity chromatography, antibody fragmentation, label conjugation, etc.) to generate highly specific reagents.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
CLL-cells induce IDOhi CD14+HLA-DRlo myeloid-derived suppressor cells that inhibit T-cell responses and promote TRegs.
A-21145 was used in immunohistochemistry - paraffin section to determine the presence, frequency, association to other immune parameters, and functional properties of circulating CD14(+) cells lacking HLA-DR expression in patients with untreated chronic lymphocytic leukemia
|Jitschin R,Braun M,Büttner M,Dettmer-Wilde K,Bricks J,Berger J,Eckart MJ,Krause SW,Oefner PJ,Le Blanc K,Mackensen A,Mougiakakos D||Blood (124:750)||2014|
|Not Applicable||Not Cited||β-Catenin-SOX2 signaling regulates the fate of developing airway epithelium.||Hashimoto S,Chen H,Que J,Brockway BL,Drake JA,Snyder JC,Randell SH,Stripp BR||Journal of cell science (125:932)||2012|
|Not Applicable||Not Cited||Role of Rac1 in regulation of NOX5-S function in Barrett's esophageal adenocarcinoma cells.||Hong J,Resnick M,Behar J,Wands J,DeLellis RA,Cao W||American journal of physiology. Cell physiology (301:C413)||2011|
|Not Applicable||Not Cited||Characterization of prefibrillar Tau oligomers in vitro and in Alzheimer disease.||Patterson KR,Remmers C,Fu Y,Brooker S,Kanaan NM,Vana L,Ward S,Reyes JF,Philibert K,Glucksman MJ,Binder LI||The Journal of biological chemistry (286:23063)||2011|
|Not Applicable||Not Cited||Functional cardiomyocytes derived from human induced pluripotent stem cells.||Zhang J,Wilson GF,Soerens AG,Koonce CH,Yu J,Palecek SP,Thomson JA,Kamp TJ||Circulation research (104:e30)||2009|
|Not Applicable||Not Cited||RbAp48 regulates cytoskeletal organization and morphology by increasing K-Ras activity and signaling through mitogen-activated protein kinase.||Scuto A,Zhang H,Zhao H,Rivera M,Yeatman TJ,Jove R,Torres-Roca JF||Cancer research (67:10317)||2007|
|Not Applicable||Not Cited||Ligand-induced down-regulation of the cannabinoid 1 receptor is mediated by the G-protein-coupled receptor-associated sorting protein GASP1.||Martini L,Waldhoer M,Pusch M,Kharazia V,Fong J,Lee JH,Freissmuth C,Whistler JL||FASEB journal : official publication of the Federation of American Societies for Experimental Biology (21:802)||2007|
|Not Applicable||Not Cited||Regulation of IGF-I receptor signaling in diabetic cardiac muscle: dysregulation of cytosolic and mitochondria HSP60.||Lai HC,Liu TJ,Ting CT,Yang JY,Huang L,Wallace D,Kaiser P,Wang PH||American journal of physiology. Endocrinology and metabolism (292:E292)||2007|
|Not Applicable||Not Cited||Magnitude of stromal hemangiogenesis correlates with histologic subtype of non-Hodgkin's lymphoma.||Ruan J,Hyjek E,Kermani P,Christos PJ,Hooper AT,Coleman M,Hempstead B,Leonard JP,Chadburn A,Rafii S||Clinical cancer research : an official journal of the American Association for Cancer Research (12:5622)||2006|
|Not Applicable||Not Cited||Coexpression of CD25 and CD27 identifies FoxP3+ regulatory T cells in inflamed synovia.||Ruprecht CR,Gattorno M,Ferlito F,Gregorio A,Martini A,Lanzavecchia A,Sallusto F||The Journal of experimental medicine (201:1793)||2005|
|Not Applicable||Not Cited||An immunocytochemical approach to detection of mitochondrial disorders.||Hanson BJ,Capaldi RA,Marusich MF,Sherwood SW||The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society (50:1281)||2002|