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|Tested species reactivity||Human|
|Published species reactivity||Pig|
|Host / Isotype||Mouse / IgG|
|Immunogen||MUC1 60 mer tandem repeats (BSA conjugated)|
|Storage buffer||0.01M HEPES, pH 7.5, with 100µg/ml BSA, 0.15M NaCl, 50% glycerol|
|Tested Applications||Dilution *|
|Flow Cytometry (Flow)||1:50|
|Immunohistochemistry (IHC)||Assay Dependent|
|Immunoprecipitation (IP)||Assay Dependent|
|Western Blot (WB)||1:1,000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Immunohistochemistry (Paraffin) (IHC (P))||See 1 publications below|
MUC-1 is a heavily O-glycosylated transmembrane protein expressed on most secretory epithelium, including mammary gland and some hematopoietic cells. It is expressed abundantly in lactating mammary glands and overexpressed abundantly in >90% breast carcinomas and metastases. Transgenic MUC-1 has been shown to associate with all four cebB receptors and localize with erbB1 (EGFR) in lactating glands.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Vocal fold ion transport and mucin expression following acrolein exposure.
A14026 was used in immunohistochemistry - paraffin section to investigate the effect of acrolein exposure on vocal fold ion transport and mucin expression
|Levendoski EE,Sivasankar MP||The Journal of membrane biology (247:441)||2014|
breast carcinoma-associated antigen DF3; cancer antigen 15-3; carcinoma-associated mucin; CD227; DF3 antigen; EMA; episialin; Epithelial Membrane Antigen; H23 antigen; KL-6; krebs von den Lungen-6; MAM6; Medullary cystic kidney disease, autosomal dominant; MUC-1/SEC; MUC-1/X; MUC1/ZD; mucin 1, transmembrane; peanut-reactive urinary mucin; PEM; polymorphic epithelial mucin; PUM; tumor associated epithelial mucin; tumor-associated epithelial membrane antigen
ADMCKD; ADMCKD1; CA 15-3; CD227; EMA; H23AG; KL-6; MAM6; MCD; MCKD; MCKD1; MUC-1; MUC-1/SEC; MUC-1/X; MUC1; MUC1/ZD; PEM; PEMT; PUM