|Tested species reactivity||Human|
|Published species reactivity||Human|
|Host / Isotype||Mouse / IgG2a, kappa|
|Immunogen||Recombinant protein encoding 5 tandem repeats of the human MUC2 apomucin|
|Storage buffer||PBS, pH 7.4, with 0.2% BSA|
|Contains||0.09% sodium azide|
|Storage Conditions||4° C|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||2-4 µg/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Immunohistochemistry (IHC)||See 9 publications below|
MA5-11240 targets Mucin 2 in IHC (P) applications and shows reactivity with Human samples.
The MA5-11240 immunogen is recombinant protein encoding 5 tandem repeats of the human MUC2 apomucin.
Secreted epithelial mucins are large macromolecules which exhibit extreme polydispersity. Mucin 2 is the major intestinal mucin. O-glycans are attached to MUC2 in a potentially diverse arrangement, which is crucial for their interaction with endogeneous and exogeneous lectins.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
The relationship among PDX1, CDX2, and mucin profiles in gastric carcinomas; correlations with clinicopathologic parameters.
MA5-11240 was used in immunohistochemistry to study the association of PDX1 expression with various clinicopathologic parameters in gastric carcinomas
|Oz Puyan F,Can N,Ozyilmaz F,Usta U,Sut N,Tastekin E,Altaner S||Journal of cancer research and clinical oncology (137:1749)||2011|
Viral hepatitis is associated with intrahepatic cholangiocarcinoma with cholangiolar differentiation and N-cadherin expression.
MA5-11240 was used in immunohistochemistry to study the association of viral hepatitis with N-cadherin-positive intrahepatic cholangiocarcinoma
|Yu TH,Yuan RH,Chen YL,Yang WC,Hsu HC,Jeng YM||Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc (24:810)||2011|
Prognostic significance of MUC1, MUC2 and MUC5AC expressions in gastric carcinoma.
MA5-11240 was used in immunohistochemistry to study the prognostic value of MUC1, MUC2 and MUC5AC in gastric carcinoma
|¿lhan Ö,Han Ü,Önal B,Çel¿k SY||The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology (21:345)||2010|
Exploring the peritoneal surface malignancy phenotype--a pilot immunohistochemical study of human pseudomyxoma peritonei and derived animal models.
MA5-11240 was used in immunohistochemistry to characterize the expression of a number of proteins in tissues from pseudomyxoma peritonei patients
|Flatmark K,Davidson B,Kristian A,Stavnes HT,Førsund M,Reed W||Human pathology (41:1109)||2010|
The use of MUC5B antibody in identifying the fungal type of fungal sinusitis.
MA5-11240 was used in immunohistochemistry to examine the diagnostic significance of MUC5B antibody in fungal sinusitis
|Piao YS,Zhang Y,Yang X,He CY,Liu HG||Human pathology (39:650)||2008|
Does HepPar-1 immunoexpression have a role in differential diagnosis of periampullary cancer?
MA5-11240 was used in immunohistochemistry to investigate the diagnostic value of HepPar-1 expression in the periampullary cancer
|Gulluoglu MG,Karayigit E,Ozden I,Kapran Y,Dizdaroglu F||Pathology (40:35)||2008|
MUC5AC, a gel-forming mucin accumulating in gallstone disease, is overproduced via an epidermal growth factor receptor pathway in the human gallbladder.
MA5-11240 was used in immunohistochemistry to investigate the overproduction of MUC5AC in gallstone disease and its mechanism
|Finzi L,Barbu V,Burgel PR,Mergey M,Kirkwood KS,Wick EC,Scoazec JY,Peschaud F,Paye F,Nadel JA,Housset C||The American journal of pathology (169:2031)||2006|
Relationship between MUC5AC and altered expression of MLH1 protein in mucinous and non-mucinous colorectal carcinomas.
MA5-11240 was used in immunohistochemistry to study the association of MUC5AC with altered expression of MLH1 protein in mucinous and non-mucinous colorectal carcinomas
|Losi L,Scarselli A,Benatti P,Ponz de Leon M,Roncucci L,Pedroni M,Borghi F,Lamberti I,Rossi G,Marino M,Ponti G,Zangardi G,Menigatti M,Di Gregorio C||Pathology, research and practice (200:371)||2004|
Primary mucinous (so-called colloid) carcinomas of the lung: a clinicopathologic and immunohistochemical study with special reference to CDX-2 homeobox gene and MUC2 expression.
MA5-11240 was used in immunohistochemistry to report the clinicopathologic and immunohistochemical features of primary mucinous carcinomas of the lung
|Rossi G,Murer B,Cavazza A,Losi L,Natali P,Marchioni A,Migaldi M,Capitanio G,Brambilla E||The American journal of surgical pathology (28:442)||2004|