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|Tested species reactivity||Dog, Chicken, Cat, Human, Mouse, Primate, Rabbit, Rat, Shrew|
|Published species reactivity||Human, Mouse|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Muscle actin, purified from human myocardium.|
|Storage buffer||tissue culture supernatant diluted in PBS with 1% BSA|
|Contains||0.1% sodium azide|
|Storage Conditions||4°C or -20°C if preferred|
|Tested Applications||Dilution *|
|Immunohistochemistry (Frozen) (IHC (F))||Assay Dependent|
|Immunohistochemistry (Paraffin) (IHC (P))||1/10 - 1/40|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
This antibody detects muscle specific alpha acti and does not recognize beta actin.
This product does not require tissue predigestion or antigen retrieval steps for immunostaining of paraffin-embedded tissues. A suggested positive control for immunohistochemical applications is skeletal tissue.
Actins are highly conserved proteins that are involved in various types of cell motility, and maintenance of the cytoskeleton. In vertebrates, three main groups of actin isoforms, alpha, beta and gamma have been identified. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. The beta and gamma actins co-exist in most cell types as components of the cytoskeleton, and as mediators of internal cell motility. Actin, gamma 2, encoded by this gene, is a smooth muscle actin found in enteric tissues.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Plexiform fibromyxoma (plexiform angiomyxoid myofibroblastic tumor) of stomach: an unusual presentation as a fistulating abscess.
MA1-82599 was used in immunohistochemistry to report on a case of plexiform fibromyxoma of the stomach
|Lee PW,Yau DT,Lau PP,Chan JK||International journal of surgical pathology (22:286)||2014|
Expression of E-cadherin in angiomyolipoma.
MA1-82599 was used in immunohistochemistry to perform a systematic study of E-cadherin expression in angiomyolipoma
|Wang Z,Gong Q,Fan Q||Human pathology (43:2348)||2012|
Sporadic haemangioblastoma of the kidney with rhabdoid features and focal CD10 expression: report of a case and literature review.
MA1-82599 was used in immunohistochemistry to report on a case of sporadic haemangioblastoma of the kidney with rhabdoid features and focal CD10 expression
|Yin WH,Li J,Chan JK||Diagnostic pathology (7:null)||2012|
Fascin expression and its potential significance in gastrointestinal stromal tumors.
MA1-82599 was used in immunohistochemistry to study the expression of fascin in gastrointestinal stromal tumors and its possible prognostic value
|Ozcan A,Karslioğlu Y,Günal A,Cermık AH,Kurt B,Ongürü O||The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology (22:363)||2011|
Tumor-in-tumor of the thyroid with basaloid differentiation: a lesion with a solid cell nest neoplastic component?
MA1-82599 was used in immunohistochemistry to report on a case of tumor-in-tumor of the thyroid with basaloid differentiation
|Eloy C,Vinagre J,Cameselle-Teijeiro J,Paiva ME,Soares P,Sobrinho-Simões M||International journal of surgical pathology (19:276)||2011|
Chorangiosis: the potential role of smoking and air pollution.
MA1-82599 was used in immunohistochemistry to investigate the role of smoking and air pollution in the development of chorangiosis
|Akbulut M,Sorkun HC,Bir F,Eralp A,Duzcan E||Pathology, research and practice (205:75)||2009|
Myointimoma of the glans penis.
MA1-82599 was used in immunohistochemistry to report on a case of myointimoma of the glans penis
|Vardar E,Gunlusoy B,Arslan M,Kececi S||Pathology international (57:158)||2007|
Ectopic cervical anaplastic ependymoma.
MA1-82599 was used in immunohistochemistry to report on a case of ectopic cervical anaplastic ependymoma
|Wang Z,Huang G,Yan P,Liang R,Wang J,Yan Q,Zhang J,Cheng H,Hu P,Ma MJ||Pathology international (55:781)||2005|
Cutaneous lymphoid hyperplasia and other lymphoid infiltrates of the breast nipple: a retrospective clinicopathologic study of fifty-six patients.
MA1-82599 was used in immunohistochemistry to study the clinicopathological spectrum of lymphoproliferations and other lymphoid infiltration of the breast nipple
|Boudova L,Kazakov DV,Sima R,Vanecek T,Torlakovic E,Lamovec J,Kutzner H,Szepe P,Plank L,Bouda J,Hes O,Mukensnabl P,Michal M||The American Journal of dermatopathology (27:375)||2005|
Epstein-Barr virus-associated smooth muscle tumour: a distinctive mesenchymal tumour of immunocompromised individuals.
MA1-82599 was used in immunohistochemistry to report on a case of Epstein-Barr virus-associated smooth muscle tumour
|Cheuk W,Li PC,Chan JK||Pathology (34:245)||2002|
G-CSF promotes the proliferation of developing cardiomyocytes in vivo and in derivation from ESCs and iPSCs.
MA1-82599 was used in immunocytochemistry to investigate the expression level of G-CSFR in vivo and the role of G-CSF during cardiomyogenesis in vitro and in vivo
|Shimoji K,Yuasa S,Onizuka T,Hattori F,Tanaka T,Hara M,Ohno Y,Chen H,Egasgira T,Seki T,Yae K,Koshimizu U,Ogawa S,Fukuda K||Cell stem cell (6:227)||2010|
Microfabrication-based modulation of embryonic stem cell differentiation.
MA1-82599 was used in immunocytochemistry to study the effect of microfabricated adhesive stencils on embryonic stem cell differentiation
|Park J,Cho CH,Parashurama N,Li Y,Berthiaume F,Toner M,Tilles AW,Yarmush ML||Lab on a chip (7:1018)||2007|
a-actin; ACTA3; ACTE; actin alpha 1; actin alpha cardiac; actin alpha cardiac 1; actin, alpha cardiac muscle 1; actin, alpha skeletal muscle; actin, alpha, cardiac 1; actin, alpha, vascular smooth muscle; actin, aortic smooth muscle; actin, gamma-enteric smooth muscle; actin-like protein; ACTL3; ACTSG; alpha-actin; alpha-actin cardiac; alpha-actin-1; alpha-actin-2; alpha-actin-3; alpha-cardiac actin; alpha-sma; alpha-smooth muscle actin; alphac-actin; cell growth-inhibiting gene 46 protein; gamma-2-actin; gamma-enteric smooth muscle actin; nemaline myopathy type 3; smooth muscle alpha-actin; smooth muscle gamma-actin
0610041G09Rik; a-SMA; AA959943; AAT6; ACT; Act-4; Act4; ACTA; Acta-2; ACTA1; ACTA2; ACTA3; ACTC; Actc-1; ACTC1; ACTE; ACTG2; ACTGE; ACTL3; Acts; ACTSA; ACTSG; Actsk-1; ACTVS; alphaSMA; ASD5; ASMA; CFTD; CFTD1; CFTDM; CMD1R; CMH11; GAMMA-ACTIN; GIG46; LVNC4; MPFD; MYMY5; NEM1; NEM2; NEM3; SHPM; SMalphaA; SMGA; VSCM
(Human) P68133, (Chicken) P68139, (Human) P62736, (Rabbit) P62740, (Chicken) P08023, (Human) P04270, (Chicken) P68034, (Human) P63267, (Chicken) P63270, (Rat) P68136, (Mouse) P68134, (Rat) P62738, (Mouse) P62737, (Mouse) P68033, (Rat) P68035, (Mouse) P63268, (Rat) P63269
(Human) 58, (Chicken) 421534, (Human) 59, (Rabbit) 100009271, (Chicken) 423787, (Human) 70, (Chicken) 423298, (Human) 72, (Chicken) 396084, (Rat) 29437, (Mouse) 11459, (Rat) 81633, (Mouse) 11475, (Mouse) 11464, (Rat) 29275, (Mouse) 11468, (Rat) 25365