The MA1-7420 antibody reacts with Mycobacter. tuberculosis 16 kDa Ag in bacterial and infected tissue samples.
MA1-7420 has been successfully used in ELISA and Western blot applications.
The MA1-7420 antibody was raised against Mycobacterium tuberculosis 16 kDa antigen.
Tuberculosis is a chronic bacterial infection which remains one of the leading killers of young adults world wide. Mycobacterium tuberculosis enters the alveoli by airborne transmission. They are engulfed by alveolar macrophages but resist destruction. Although the exact mechanism is not known, it is suspected that that Mycrobacterium tuberculosis survives by preventing the fusion of the phagosome and lysosome. As the bacterium accumulates it forms a tubercle, spreads to the lymph nodes and becomes a systemic infection. Although treatments for tuberculosis do exist, new strains of Mycobacterium tuberculosis that appear to have multiple-drug resistance (MDR) pose a considerable threat to public health.
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Protein Aliases: M. tuberculosis; myobacter