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Product Details
MA1-35712
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgM
Class
Monoclonal
Type
Antibody
Clone
2B5
Immunogen
Human myelin isolated from peripheral nervous system
Conjugate
Form
Liquid
Concentration
Conc. Not Determined
Storage buffer
ascites
Contains
0.09% sodium azide
Storage conditions
4° C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_1077019
Product Specific Information
In paraffin sections antibody pm 43 recognizes only myelin in the peripheral nervous system (PNS). In frozen sections it also reacts with myelin in the central nervous system (CNS). Is useful for studying myelination and demyelination processes in the PNS, and remyelination processes in the CNS as can be observed after trauma in multiple sclerosis. Reacts with a 43 kD protein in immunoblotting.
Positive control: Peripheral nerve.
Target Information
Myelin is a membrane characteristic of the nervous tissue and functions as an insulator to increase the velocity of the stimuli being transmitted between a nerve cell body and its target. Myelin isolated from human and bovine nervous tissue is composed of approximately 80% lipid and 20% protein, and 30% of the protein fraction constitutes myelin basic protein.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: MGC99675
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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