|Tested species reactivity||Human|
|Host / Isotype||Sheep / IgG|
|Immunogen||Synthetic peptide corresponding to residues Y(68) G S L P Q K S Q R S Q D E N P V V(86) of guinea pig MBP.|
|Storage buffer||whole serum|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA1-18319 detects MBP from human samples.
PA1-18319 has been successfully used in immunohistochemistry procedures.
The PA1-18319 immunogen is a synthetic peptide corresponding to residues Y(68) G S L P Q K S Q R S Q D E N P V V(86) of guinea pig MBP, conjugated to KLH.
Reconstitute with 100 ul of distilled water.
Myelin is a membrane characteristic of the nervous tissue and functions as an insulator to increase the velocity of the stimuli being transmitted between a nerve cell body and its target. Myelin isolated from human and bovine nervous tissue is composed of approximately 80% lipid and 20% protein, and 30% of the protein fraction constitutes myelin basic protein. MBP is an 'intrinsically unstructured' protein with a high proportion (approximately 75%) of random coil, but postulated to have core elements of beta-sheet and alpha-helix. MBP is a major protein in CNS myelin and is expressed specifically in the nervous system.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.