|Tested species reactivity||Human, Mouse, Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Residues 49-62 of human, mouse and rat MBP protein.|
|Purification||Antigen affinity chromatography|
|Contains||0.02% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:200|
|Western Blot (WB)||1:500-1:1000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
The PA1-46447 immunogen corresponds to residues 49-62 of Isoforms 5 and 6 of the human protein.
The immunogen corresponds to Isoform 1 between amino acids 182-195 of the 33 kDa isoform.
This antibody also detects mouse and rat MBP protein.Suggested positive control: normal human brain lysate.
Myelin Basic Protein (MBP) functions in the nervous system in myelination and is expressed in oligodendrocytes following differentiation. There are numerous isoforms generated by differential splicing events and post-translational modifications that have specialized functions. These functions include participation in signaling pathways prior to myelination, myelination or the re-myelination process following neural injury.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.