Product References
A Uterus-Inspired Niche Drives Blastocyst Development to the Early Organogenesis.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Gu Z,Guo J,Zhai J,Feng G,Wang X,Gao Z,Li K,Ji S,Wang L,Xu Y,Chen X,Wang Y,Guo S,Yang M,Li L,Han H,Jiang L,Wen Y,Wang L,Hao J,Li W,Wang S,Wang H,Gu Q
53-6503-82 was used in Immunocytochemistry-immunofluorescence to establish a uterus-inspired niche (UN) by grafting collagen gels onto polydimethylsiloxane, systematically varying concentrations and thicknesses of collagen gel to mimic the mechanical properties and microstructures of the mouse uterus, resulting in a robust system that supports embryo invasion and promotes early organogenesis, offering a valuable tool for developmental biology and tissue engineering.
Sat Oct 01 00:00:00 EDT 2022
TAM kinase signaling is indispensable for proper skeletal muscle regeneration in mice.
Cell death & disease
Al-Zaeed N,Budai Z,Szondy Z,Sarang Z
Published figure using Myosin 4 monoclonal antibody (Product # 53-6503-82) in Western Blot
Sat Jun 12 00:00:00 EDT 2021
TAM kinase signaling is indispensable for proper skeletal muscle regeneration in mice.
Cell death & disease
Al-Zaeed N,Budai Z,Szondy Z,Sarang Z
Published figure using Myosin 4 monoclonal antibody (Product # 53-6503-82) in Western Blot
Sat Jun 12 00:00:00 EDT 2021
Impaired Skeletal Muscle Development and Regeneration in Transglutaminase 2 Knockout Mice.
Cells
Budai Z,Al-Zaeed N,Szentesi P,Halász H,Csernoch L,Szondy Z,Sarang Z
Published figure using Myosin 4 monoclonal antibody (Product # 53-6503-82) in Western Blot
Tue Nov 09 00:00:00 EST 2021
Impaired Skeletal Muscle Development and Regeneration in Transglutaminase 2 Knockout Mice.
Cells
Budai Z,Al-Zaeed N,Szentesi P,Halász H,Csernoch L,Szondy Z,Sarang Z
Published figure using Myosin 4 monoclonal antibody (Product # 53-6503-82) in Western Blot
Tue Nov 09 00:00:00 EST 2021
In vivo detection of programmed cell death during mouse heart development.
Cell death and differentiation
Martínez-Lagunas K,Yamaguchi Y,Becker C,Geisen C,DeRuiter MC,Miura M,Fleischmann BK,Hesse M
Published figure using Myosin 4 monoclonal antibody (Product # 53-6503-82) in Immunohistochemistry
Wed Apr 01 00:00:00 EDT 2020
Comprehensive histological investigation of age-related changes in dermal extracellular matrix and muscle fibers in the upper lip vermilion.
International journal of cosmetic science
Gomi T,Imamura T
53-6503 was used in Immunohistochemistry-immunofluorescence to collect and study histological and molecular data on age-dependent alterations in the upper lip vermillion.
Sat Aug 01 00:00:00 EDT 2020
TAK-242, a specific inhibitor of Toll-like receptor 4 signalling, prevents endotoxemia-induced skeletal muscle wasting in mice.
Scientific reports
Ono Y,Maejima Y,Saito M,Sakamoto K,Horita S,Shimomura K,Inoue S,Kotani J
Published figure using Myosin 4 monoclonal antibody (Product # 53-6503-82) in Western Blot
Mon Jan 20 00:00:00 EST 2020
TAK-242, a specific inhibitor of Toll-like receptor 4 signalling, prevents endotoxemia-induced skeletal muscle wasting in mice.
Scientific reports
Ono Y,Maejima Y,Saito M,Sakamoto K,Horita S,Shimomura K,Inoue S,Kotani J
Published figure using Myosin 4 monoclonal antibody (Product # 53-6503-82) in Western Blot
Mon Jan 20 00:00:00 EST 2020
Data on the proliferation and differentiation of C2C12 myoblast treated with branched-chain ketoacid dehydrogenase kinase inhibitor.
Data in brief
Sato Y,Tate H,Yoshizawa F,Sato Y
Published figure using Myosin 4 monoclonal antibody (Product # 53-6503-82) in Western Blot
Sat Aug 01 00:00:00 EDT 2020
hiPSC-Derived Neurons Provide a Robust and Physiologically Relevant In Vitro Platform to Test Botulinum Neurotoxins.
Frontiers in pharmacology
Lamotte JD,Roqueviere S,Gautier H,Raban E,Bouré C,Fonfria E,Krupp J,Nicoleau C
Published figure using Myosin 4 monoclonal antibody (Product # 53-6503-82) in Immunocytochemistry
Tue Feb 02 00:00:00 EST 2021
Assessment of different strategies for scalable production and proliferation of human myoblasts.
Cell proliferation
Chua MJ,Yildirim ED,Tan JE,Chua YB,Low SC,Ding SLS,Li CW,Jiang Z,Teh BT,Yu K,Shyh-Chang N
53-6503 was used in Immunocytochemistry-immunoflourescence to show that, while all the strategies above are suboptimal at generating bona fide human myoblasts that can both proliferate and differentiate robustly, chemically defined hESC-monolayer-myoblasts show the most promise in differentiation potential.
Wed May 01 00:00:00 EDT 2019
Micropatterned substrates with physiological stiffness promote cell maturation and Pompe disease phenotype in human induced pluripotent stem cell-derived skeletal myocytes.
Biotechnology and bioengineering
Jiwlawat N,Lynch EM,Napiwocki BN,Stempien A,Ashton RS,Kamp TJ,Crone WC,Suzuki M
53-6503-82 was used in Immunohistochemistry to demonstrate that human induced pluripotent stem cell (iPSC)-derived myogenic progenitors formed highly-aligned myotubes and contracted when seeded on two-dimensional micropatterned platforms.
Sun Sep 01 00:00:00 EDT 2019
Peptidyl-prolyl cis-trans isomerase NIMA interacting 1 regulates skeletal muscle fusion through structural modification of Smad3 in the linker region.
Journal of cellular physiology
Islam R,Yoon H,Shin HR,Bae HS,Kim BS,Yoon WJ,Woo KM,Baek JH,Lee YS,Ryoo HM
Published figure using Myosin 4 monoclonal antibody (Product # 53-6503-82) in Immunocytochemistry
Sat Dec 01 00:00:00 EST 2018
Classification of C2C12 cells at differentiation by convolutional neural network of deep learning using phase contrast images.
Human cell
Niioka H,Asatani S,Yoshimura A,Ohigashi H,Tagawa S,Miyake J
53-6503 was used in Immunocytochemistry to develop the convolutional neural network algorithm for automatic cellular differentiation recognition of the myogenic C12C12 cell line.
Mon Jan 01 00:00:00 EST 2018
Ternary Aligned Nanofibers of RGD Peptide-Displaying M13 Bacteriophage/PLGA/Graphene Oxide for Facilitated Myogenesis.
Nanotheranostics
Shin YC,Kim C,Song SJ,Jun S,Kim CS,Hong SW,Hyon SH,Han DW,Oh JW
53-6503 was used in Immunocytochemistry-immunoflourescence to fabricate poly(lactic-co-glycolic acid) nanofibre sheets decorated with graphene oxide and RGD peptid, as biofunctional scaffolds.
Wed Nov 20 00:00:00 EST 2019
NOTCH1-Dependent Nitric Oxide Signaling Deficiency in Hypoplastic Left Heart Syndrome Revealed Through Patient-Specific Phenotypes Detected in Bioengineered Cardiogenesis.
Stem cells (Dayton, Ohio)
Hrstka SC,Li X,Nelson TJ
53-6503 was used in Immunocytochemistry-immunoflourescence to study a mechanistic basis through which NOTCH1 contributes to heart development.
Sat Apr 01 00:00:00 EDT 2017
An Engineered Optogenetic Switch for Spatiotemporal Control of Gene Expression, Cell Differentiation, and Tissue Morphogenesis.
ACS synthetic biology
Polstein LR,Juhas M,Hanna G,Bursac N,Gersbach CA
53-6503 was used in Immunocytochemistry-immunofluorescence to apply optogenetics to control cell differentiation and new tissue formation.
Fri Nov 17 00:00:00 EST 2017
Targeted Ablation of Periostin-Expressing Activated Fibroblasts Prevents Adverse Cardiac Remodeling in Mice.
Circulation research
Kaur H,Takefuji M,Ngai CY,Carvalho J,Bayer J,Wietelmann A,Poetsch A,Hoelper S,Conway SJ,Möllmann H,Looso M,Troidl C,Offermanns S,Wettschureck N
53-6503 was used in Immunohistochemistry to study the effect of activated cardiac fibroblast ablation on cardiac remodeling.
Fri Jun 10 00:00:00 EDT 2016
Natural underlying mtDNA heteroplasmy as a potential source of intra-person hiPSC variability.
The EMBO journal
Perales-Clemente E,Cook AN,Evans JM,Roellinger S,Secreto F,Emmanuele V,Oglesbee D,Mootha VK,Hirano M,Schon EA,Terzic A,Nelson TJ
53-6503 was used in Flow cytometry/Cell sorting to characterise the mitochondrial DNA of human induced pluripotent stem cells for use as a selection criteria.
Thu Sep 15 00:00:00 EDT 2016
Ultrastructure of medial rectus muscles in patients with intermittent exotropia.
Eye (London, England)
Yao J,Wang X,Ren H,Liu G,Lu P
Published figure using Myosin 4 monoclonal antibody (Product # 53-6503-82) in Western Blot
Fri Jan 01 00:00:00 EST 2016
Single-molecule analysis of myocyte differentiation reveals bimodal lineage commitment.
Integrative biology : quantitative biosciences from nano to macro
Gibson TM,Gersbach CA
Published figure using Myosin 4 monoclonal antibody (Product # 53-6503-82) in Immunofluorescence
Mon Jun 01 00:00:00 EDT 2015
Single-molecule analysis of myocyte differentiation reveals bimodal lineage commitment.
Integrative biology : quantitative biosciences from nano to macro
Gibson TM,Gersbach CA
Published figure using Myosin 4 monoclonal antibody (Product # 53-6503-82) in Immunofluorescence
Mon Jun 01 00:00:00 EDT 2015
iPS cell-derived cardiogenicity is hindered by sustained integration of reprogramming transgenes.
Circulation. Cardiovascular genetics
Martinez-Fernandez A,Nelson TJ,Reyes S,Alekseev AE,Secreto F,Perez-Terzic C,Beraldi R,Sung HK,Nagy A,Terzic A
Published figure using Myosin 4 monoclonal antibody (Product # 53-6503-82) in Flow Cytometry
Wed Oct 01 00:00:00 EDT 2014
iPS cell-derived cardiogenicity is hindered by sustained integration of reprogramming transgenes.
Circulation. Cardiovascular genetics
Martinez-Fernandez A,Nelson TJ,Reyes S,Alekseev AE,Secreto F,Perez-Terzic C,Beraldi R,Sung HK,Nagy A,Terzic A
Published figure using Myosin 4 monoclonal antibody (Product # 53-6503-82) in Flow Cytometry
Wed Oct 01 00:00:00 EDT 2014
iPS cell-derived cardiogenicity is hindered by sustained integration of reprogramming transgenes.
Circulation. Cardiovascular genetics
Martinez-Fernandez A,Nelson TJ,Reyes S,Alekseev AE,Secreto F,Perez-Terzic C,Beraldi R,Sung HK,Nagy A,Terzic A
Published figure using Myosin 4 monoclonal antibody (Product # 53-6503-82) in Flow Cytometry
Wed Oct 01 00:00:00 EDT 2014
Inhibition of TGFβ signaling increases direct conversion of fibroblasts to induced cardiomyocytes.
PloS one
Ifkovits JL,Addis RC,Epstein JA,Gearhart JD
Published figure using Myosin 4 monoclonal antibody (Product # 53-6503-82) in Immunocytochemistry
Tue Jan 20 00:00:00 EST 2015
Optimization of direct fibroblast reprogramming to cardiomyocytes using calcium activity as a functional measure of success.
Journal of molecular and cellular cardiology
Addis RC,Ifkovits JL,Pinto F,Kellam LD,Esteso P,Rentschler S,Christoforou N,Epstein JA,Gearhart JD
Published figure using Myosin 4 monoclonal antibody (Product # 53-6503-82) in Immunocytochemistry
Mon Jul 01 00:00:00 EDT 2013
Optimization of direct fibroblast reprogramming to cardiomyocytes using calcium activity as a functional measure of success.
Journal of molecular and cellular cardiology
Addis RC,Ifkovits JL,Pinto F,Kellam LD,Esteso P,Rentschler S,Christoforou N,Epstein JA,Gearhart JD
Published figure using Myosin 4 monoclonal antibody (Product # 53-6503-82) in Immunocytochemistry
Mon Jul 01 00:00:00 EDT 2013