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|Tested species reactivity||Chicken , Rat|
|Host / Isotype||Rabbit / IgG1|
|Immunogen||Synthetic peptide, conjugated to KLH, corresponding to residues 1782-1799 of chicken MYO5A.|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7.4, with 1% BSA|
|Contains||15mM sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||1:200|
|Western Blot (WB)||1:1000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA1-24947 detects MYO5A from rat and chicken samples. PA1-24947 will not react with mouse.
PA1-24947 has been successfully used in Western blot procedures.
The PA1-24947 immunogen is a synthetic peptide, conjugated to KLH, corresponding to residues 1782-1799 of chicken MYO5A.
This gene is one of three myosin V heavy-chain genes, belonging to the myosin gene superfamily. Myosin V is a class of actin-based motor proteins involved in cytoplasmic vesicle transport and anchorage, spindle-pole alignment and mRNA translocation. The protein encoded by this gene is abundant in melanocytes and nerve cells. Mutations in this gene cause Griscelli syndrome type-1 (GS1), Griscelli syndrome type-3 (GS3) and neuroectodermal melanolysosomal disease, or Elejalde disease. Multiple alternatively spliced transcript variants encoding different isoforms have been reported, but the full-length nature of some variants has not been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
dilute myosin heavy chain, non-muscle; dilute-opisthotonus; MYH12; MYO5; myosin 5A; myosin heavy chain P190; myosin I heavy chain isoform; myosin VA (heavy chain 12, myoxin); myosin VA (heavy polypeptide 12, myoxin); myosin-V; myosin-Va; MYR12; unconventional myosin-Va
D; DILUTE; Dop; Myh12; MYO5A; myoxin); non-muscle