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|Tested species reactivity||Human|
|Published species reactivity||Human|
|Host / Isotype||Mouse / IgG1, kappa|
|Immunogen||Crude human uterus extract|
|Storage buffer||PBS, pH 7.4, with 0.2% BSA|
|Contains||0.09% sodium azide|
|Storage Conditions||4° C|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||1:25|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Immunohistochemistry (IHC)||See 4 publications below|
MA5-11648 targets Myosin Smooth Muscle Heavy Chain in IHC (P) applications and shows reactivity with Human samples.
The MA5-11648 immunogen is crude human uterus extract.
SM-MHC is a cytoplasmic structural protein, which is a major component of the contractile apparatus in smooth muscle cells. Expression of smooth muscle myosin is developmently regulated, appearing early in smooth muscle development, and is specific for smooth muscle development. Two isoforms of smooth muscle myosin heavy chain have been identified, designated MHC-1 and MHC-2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Immunohistochemistry in the diagnosis of papillary lesions of the breast.
MA5-11648 was used in immunohistochemistry to establish a diagnostic immunohistochemical marker panel applicable to breast papilliary lesions
|Tse GM,Ni YB,Tsang JY,Shao MM,Huang YH,Luo MH,Lacambra MD,Yamaguchi R,Tan PH||Histopathology (65:839)||2014|
Cholesterol in human atherosclerotic plaque is a marker for underlying disease state and plaque vulnerability.
MA5-11648 was used in immunohistochemistry to study plaque cholesterol as a marker for underlying disease state and atherosclerotic plaque vulnerability
|Chen Z,Ichetovkin M,Kurtz M,Zycband E,Kawka D,Woods J,He X,Plump AS,Hailman E||Lipids in health and disease (9:null)||2010|
The role of immunohistochemistry for smooth-muscle actin, p63, CD10 and cytokeratin 14 in the differential diagnosis of papillary lesions of the breast.
MA5-11648 was used in immunohistochemistry to study the immunohistochemical differentiation of breast papilliary lesions
|Tse GM,Tan PH,Lui PC,Gilks CB,Poon CS,Ma TK,Law BK,Lam WW||Journal of clinical pathology (60:315)||2007|
Soft tissue sacrococcygeal chordoma with intracytoplasmic filamentous inclusions.
MA5-11648 was used in immunohistochemistry to report on a case of soft tissue sacrococcygeal chordoma with intracytoplasmic filamentous inclusions
|Guarino M,Ballabio G,Rubino B,Nebuloni M,Tosoni A||Pathology, research and practice (201:699)||2005|
heavy polypeptide 11; myosin; myosin heavy chain; myosin heavy chain 11; myosin heavy chain, smooth muscle isoform; myosin, heavy chain 11, smooth muscle; myosin, heavy polypeptide 11, smooth muscle; myosin-11; smooth muscle; smooth muscle isoform
AAT4; FAA4; KIAA0866; MYH11; SMHC; SMMHC