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|Tested species reactivity||Human , Mouse , Rat|
|Published species reactivity||Human|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Purified recombinant fragment of human CDH2 expressed in E. Coli.|
|Contains||0.03% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Flow Cytometry (Flow)||1/200 - 1/400|
|Immunofluorescence (IF)||1/200 - 1/1000|
|Immunohistochemistry (IHC)||1/200 - 1/1000|
|Western Blot (WB)||1/500 - 1/2000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Western Blot (WB)||See 1 publications below|
MA5-15633 targets CDH2 in FACS, IF, IHC, and WB applications and shows reactivity with Human, mouse, and Rat samples.
The MA5-15633 immunogen is purified recombinant fragment of human CDH2 expressed in E. Coli.
MA5-15633 detects CDH2 which has a predicted molecular weight of approximately 99.8kDa.
This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. The protein functions during gastrulation and is required for establishment of left-right asymmetry. At certain central nervous system synapses, presynaptic to postsynaptic adhesion is mediated at least in part by this gene product.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Baicalein inhibits migration and invasion of gastric cancer cells through suppression of the TGF-β signaling pathway.
MA5-15633 was used in western blot to demonstrate that baicalein inhibits metastasis of cancer cells via inactivation of TGF-beta/Smad4 signaling
|Chen F,Zhuang M,Peng J,Wang X,Huang T,Li S,Lin M,Lin H,Xu Y,Li J,Chen Z,Huang Y||Molecular medicine reports (10:1999)||2014|
cadherin 2 type 1 N-cadherin (neuronal); cadherin 2, type 1, N-cadherin (neuronal); cadherin-2; calcium-dependent adhesion protein, neuronal; CD325; CDHN; CDw325 antigen; N-cadherin 1; NCAD; neural cadherin
CD325; CDH2; CDHN; CDw325; N-cadherin; NCAD