Rockland

NAG-1 Polyclonal Antibody, Biotin

Product Details

210-406-B68

Applications	Tested Dilution	Publications
Western Blot (WB)	1:2,000-1:10,000	-
Immunohistochemistry (IHC)	1:1,000-1:5,000	-
ELISA (ELISA)	1:20,000-1:100,000	-
Immunoprecipitation (IP)	1:2,000-1:10,000	-

Product Specifications
Species Reactivity	Human, Mouse
Host/Isotype	Rabbit / IgG
Class	Polyclonal
Type	Antibody
Immunogen	This Protein-A purified antibody was prepared by repeated immunizations with an MBP-tagged recombinant protein produced in E.coli corresponding to full-length mouse NAG-1 protein. Cross reactivity to MBP was removed via cross-adsorption chromatography. View antigen
Conjugate	Biotin
Form	Lyophilized
Concentration	1 mg/mL
Purification	Protein A
Storage buffer	0.02M potassium phosphate, pH 7.2, with 0.15M NaCl, 10mg/mL BSA
Contains	0.01% sodium azide
Storage conditions	Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Product Specific Information

Store vial at 4° C prior to restoration. For extended storage aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

This antibody reacts with endogenous NAG-1 protein from mouse and human tissues. A BLAST analysis suggests reactivity with NAG-1 from rat based on 100% homology. Partial reactivity is expected against swine, bovine and dog based on 92% homology. Cross-reactivity with NAG-1 from other sources has not been determined.

Target Information

Bone morphogenetic proteins (e. g., BMP5, MIM 112265) are members of the transforming growth factor-beta (see TGFB1, MIM 190180) superfamily and regulate tissue differentiation and maintenance. They are synthesized as precursor molecules that are processed at a dibasic cleavage site to release C-terminal domains containing a characteristic motif of 7 conserved cysteines in the mature protein.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

References (0)

Have you cited this product in a publication?

Let us know so we can reference it here.

Cite this product

Bioinformatics

Protein Aliases: GDF-15; Growth/differentiation factor 15; macrophage inhibiting cytokine-1; Macrophage inhibitory cytokine 1; MIC-1; NAG-1; NAG1; NRG-1; NSAID (nonsteroidal anti-inflammatory drug)-activated protein 1; NSAID-activated gene 1 protein; NSAID-regulated gene 1 protein; Placental bone morphogenetic protein; Placental TGF-beta; Prostate differentiation factor; PTGF-beta

Gene Aliases: GDF-15; GDF15; MIC-1; MIC1; NAG-1; PDF; PLAB; PTGFB; SBF

UniProt ID: (Human) Q99988, (Mouse) Q9Z0J7

Entrez Gene ID: (Human) 9518, (Mouse) 23886

Molecular Function: growth factor