Immunogen sequence: LLDTYSVWRS GLPNFLAVAL ALGELGYRAV GVRLDSGDLL QQAQEIRKVF RAAAAQFQVP WLESVLIVVS NNIDEEALAR LAQEGSEVNV IGIGTSV
Highest antigen sequence identity to the following orthologs: Mouse - 86%, Rat - 82%.
Binds to an epitope located within the peptide sequence IRKVFRAAAA as determined by overlapping synthetic peptides.
Nicotinic acid (NA; niacin) is converted by nicotinic acid phosphoribosyltransferase (NAPRT; EC 188.8.131.52) to NA mononucleotide (NaMN), which is then converted to NA adenine dinucleotide (NaAD), and finally to nicotinamide adenine dinucleotide (NAD), which serves as a coenzyme in cellular redox reactions and is an essential component of a variety of processes in cellular metabolism including response to stress (Hara et al., 2007).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: FHA-HIT-interacting protein; NAPRTase; Nicotinate phosphoribosyltransferase; nicotinate phosphoribosyltransferase domain containing 1; Nicotinate phosphoribosyltransferase domain-containing protein 1; nicotinic acid phosphoribosyltransferase
Gene Aliases: FHIP; NAPRT; NAPRT1; PP3856
UniProt ID: (Human) Q6XQN6
Entrez Gene ID: (Human) 93100