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Immunogen sequence: EAVSLLEEVI TPRKDLPPLL LKLNERPAER LDYLGVSYGL TPRLLKFWKR AGFVPVYLRQ TPNDLTGEHS CIMLKTLTDE DEADQGGWLA AFWKDFRRRF LALLSYQFST FSPSLALNII QNRNMGKPAQ PALSREELEA LFLPYDLKRL EMYSRNMVDY HLIMDMIPAI SRIYFLNQLG DLALSAAQSA LLLGIGLQHK SVDQLEKEIE LPSGQLMGLF NRIIRKVVKL FNEVQEKAIE EQMVAAKDVV MEPTMKTLSD DLDEAAKEFQ EKHKKEVGKL KSMDLSEYII RGDDEEWNEV LNKAGPNASI ISLKSDKKRK LEAKQEPKQS KKLKNRETKN KKDMKLKRKK
IRS4 encodes the insulin receptor substrate 4, a cytoplasmic protein that contains many potential tyrosine and serine/threonine phosphorylation sites. Tyrosine-phosphorylated IRS4 protein has been shown to associate with cytoplasmic signalling molecules that contain SH2 domains. The IRS4 protein is phosphorylated by the insulin receptor tyrosine kinase upon receptor stimulation.
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Protein Aliases: 18S rRNA cytosine acetyltransferase; hALP; N-acetyltransferase 10; N-acetyltransferase 10 (GCN5-related); N-acetyltransferase-like protein; novel putative ATPase domain containing protein; RNA cytidine acetyltransferase
Gene Aliases: AI429152; ALP; KIAA1709; NAT10; NET43; RGD1306717
UniProt ID: (Human) Q9H0A0, (Mouse) Q8K224
Entrez Gene ID: (Human) 55226, (Mouse) 98956, (Rat) 311257
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