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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||A synthetic peptide derived from the internal region of human NBPF1/9/10/12/14/15/16/20|
|Purification||Antigen affinity chromatography|
|Storage buffer||Dulbecco's PBS, pH 7.4, with 150mM NaCl, 50% glycerol|
|Contains||0.02% sodium azide|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:500-1:1000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
This antibody detects NBPF1, NBPF9, NBPF10, NBPF12, NBPF14, NBPF15, NBPF16 and NBPF20.
This gene is a member of the neuroblastoma breakpoint family (NBPF) which consists of dozens of recently duplicated genes primarily located in segmental duplications on human chromosome 1. This gene family has experienced its greatest expansion within the human lineage and has expanded, to a lesser extent, among primates in general. Members of this gene family are characterized by tandemly repeated copies of DUF1220 protein domains. Gene copy number variations in the human chromosomal region 1q21.1, where most DUF1220 domains are located, have been implicated in a number of developmental and neurogenetic diseases such as microcephaly, macrocephaly, autism, schizophrenia, mental retardation, congenital heart disease, neuroblastoma, and congenital kidney and urinary tract anomalies. Altered expression of some gene family members is associated with several types of cancer. This gene family contains numerous pseudogenes. [provided by RefSeq, Apr 2013].
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
AE5; chomosome one amplified sequence 1 cyclophilin; chromosome 1 amplified sequence 1; NBFP10; NBFP12; NBFP14; NBFP15; NBFP16; NBFP20; NBFP9; NBPF1; Neuroblastoma breakpoint family member 10; Neuroblastoma breakpoint family member 12; Neuroblastoma breakpoint family member 14; neuroblastoma breakpoint family member 16; Neuroblastoma breakpoint family member 9; neuroblastoma breakpoint family, member 1; neuroblastoma breakpoint family, member 10; neuroblastoma breakpoint family, member 12; neuroblastoma breakpoint family, member 14; neuroblastoma breakpoint family, member 15; neuroblastoma breakpoint family, member 16; neuroblastoma breakpoint family, member 20
AB13; AB14; AB23; AB6; AD2; AE01; AG1; AG3; COAS1; DJ328E19.C1.1; KIAA1245; KIAA1693; NBG; NBPF; NBPF1; NBPF15; NBPF16; NBPF20; NBPF9