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Abnova
NCOA1 Recombinant Rabbit Monoclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
RAB01713
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Expression System
CHO cells
Class
Recombinant Monoclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to human SRC1.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Purification
Affinity chromatography
Storage buffer
50mM tris glycine, pH 7.4, with 0.05% BSA, 40% glycerol, 150mM NaCl
Contains
0.01% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
Clone 1135 recognizes SRC-1, steroid-receptor coactivator-1. SRC-1 is a member of a gene family that functions in the full transcriptional activation of the steroid hormone receptor superfamily and contains intrinsic histone acetyltransferase activity. SRC-1 has a molecular weight of 160 kDa and has a basic helix-loop-helix (bHLH)-PAS domain.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ASV; c-SRC; class E basic helix-loop-helix protein 74; Hin-2; Hin-2 protein; p60-Src; renal carcinoma antigen NY-REN-52; SRC-1; SRC-1 (-Q); steroid receptor coactivator-1; unnamed protein product
Gene Aliases: bHLHe42; bHLHe74; F-SRC-1; KAT13A; RIP160; SRC1
UniProt ID: (Human) Q15788
Entrez Gene ID: (Human) 8648
RNA polymerase II regulatory region sequence-specific DNA binding
DNA binding
chromatin binding
transcription cofactor activity
transcription coactivator activity
protein binding
ligand-dependent nuclear receptor binding
estrogen receptor binding
retinoic acid receptor binding
macromolecular complex binding
retinoid X receptor binding
protein dimerization activity
peptide-lysine-N-acetyltransferase activity
positive regulation of transcription from RNA polymerase II promoter by galactose
regulation of transcription, DNA-templated
lactation
male gonad development
response to hormone
bile acid and bile salt transport
cerebellum development
hippocampus development
hypothalamus development
cerebral cortex development
intracellular estrogen receptor signaling pathway
response to estradiol
response to retinoic acid
response to progesterone
cellular response to hormone stimulus
peroxisome proliferator activated receptor signaling pathway
mRNA transcription from RNA polymerase II promoter
positive regulation of apoptotic process
estrous cycle
positive regulation of neuron differentiation
positive regulation of transcription, DNA-templated
positive regulation of female receptivity
positive regulation of transcription from RNA polymerase II promoter
progesterone receptor signaling pathway
male mating behavior
regulation of cellular response to insulin stimulus
positive regulation of adipose tissue development
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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