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|Tested species reactivity||Human|
|Host / Isotype||Mouse / IgG|
|Immunogen||Fusion protein, corresponding to amino acids 605-1294 of Human NCOA3.|
|Contains||0.05% sodium azide|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Immunoprecipitation (IP)||20 µl/mg cell lysate|
|Western Blot (WB)||1:1000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
MA1-91854 detects NCOA3 from human samples.
MA1-91854 has been successfully used in immunoprecipitation, Western blot applications.
The MA1-91854 immunogen is: Fusion protein, corresponding to amino acids 605-1294 of Human NCOA3.
The protein encoded by this gene is a nuclear receptor coactivator that interacts with nuclear hormone receptors to enhance their transcriptional activator functions. The encoded protein has histone acetyltransferase activity and recruits p300/CBP-associated factor and CREB binding protein as part of a multisubunit coactivation complex. This protein is initially found in the cytoplasm but is translocated into the nucleus upon phosphorylation. Two transcript variants encoding different isoforms have been found for this gene. In addition, a polymorphic repeat region is found in the C-terminus of the encoded protein.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
AIB-1; AIB1; amplified in breast cancer 1 protein; bHLHe42; CAGH16; CBP-interacting protein; class E basic helix-loop-helix protein 42; CTG26; KAT13B; MGC141848; pCIP; RAC3; receptor-associated coactivator 3; RP5-1049G16.3; SRC-3; SRC3; steroid receptor coactivator protein 3; thyroid hormone receptor activator molecule 1; TNRC14; TNRC16; TRAM-1
ACTR; AIB-1; AIB1; BHLHE42; CAGH16; CTG26; KAT13B; NCOA3; pCIP; RAC3; SRC-3; SRC3; TNRC14; TNRC16; TRAM-1; TRAM1