|Tested species reactivity||Human|
|Host / Isotype||Mouse / IgG|
|Immunogen||Fusion protein corresponding to residues 605-1294 of human NCOA3.|
|Storage buffer||Ascites with 30% glycerol|
|Contains||0.035% sodium azide|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Immunoprecipitation (IP)||15 µl|
|Western Blot (WB)||1:500|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
MA1-25420 detects NCOA3 from human samples.
MA1-25420 has been successfully used in Western blot procedures.
The MA1-25420 immunogen is a fusion protein corresponding to residues 605-1294 of human NCOA3.
The protein encoded by this gene is a nuclear receptor coactivator that interacts with nuclear hormone receptors to enhance their transcriptional activator functions. The encoded protein has histone acetyltransferase activity and recruits p300/CBP-associated factor and CREB binding protein as part of a multisubunit coactivation complex. This protein is initially found in the cytoplasm but is translocated into the nucleus upon phosphorylation. Two transcript variants encoding different isoforms have been found for this gene. In addition, a polymorphic repeat region is found in the C-terminus of the encoded protein.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.