Sequence of this protein is as follows: QQQTLPKPFI WAEPHFMVPK EKQVTICCQG NYGAVEYQLH FEGSLFAVDR PKPPERINKV KFYIPDMNSR MAGQYSCIYR VGELWSEPSN LLDLVVTEMY DTPTLSVHPG PEVISGEKVT FYCRLDTATS MFLLLKEGRS SHVQRGYGKV QAEFPLGPVT TAHRGTYRCF GSYNNHAWSF PSEPVKLLVT GDIENTSLAP EDPTFPDTWG TYLLTTETGL QKDHALWDHT AQNLLRMGLA FLVLVALVWF LVEDWLSRKR TRERASRAST WEGRRRLNTQ TL
NKp46 (CD335, NCR1, ) is a cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis. NKp46 consists of two Ig-like domains assembled to leukocyte immunoglobulin-like (LIR) and killer inhibitory receptors (KIR).
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Protein Aliases: 1-Mar; CD335; hNKp46; Ly-94; Lymphocyte antigen 94 homolog; lymphocyte antigen 94 homolog (activating NK-receptor; NK-p46); Natural cytotoxicity triggering receptor 1; Natural killer cell p46-related protein; natural killer cell receptor; NK cell-activating receptor; NK-p46
Gene Aliases: CD335; LY94; NCR1; NK-p46; NKP46
UniProt ID: (Human) O76036
Entrez Gene ID: (Human) 9437
Molecular Function: immunoglobulin receptor superfamily