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NCS1 Antibody (ACS-001-50UL) in IHC (F)
Expression ofNCS1 in mouse cerebellum. Immunohistochemicalstaining of perfusion-fixed frozenmouse brainsections with Anti-NCS1 Antibody (#ACS-001), (1:100), followed bygoat Anti-rabbit-Alexa-488.A.NCS1immunoreactivity (green)appeared inthe Purkinje layer (P, horizontal arrow) and inpurkinjedendrites (vertical arrow) in the molecular layer (MOL).B. Pre-incubation of the Antibody with NCS1Blocking Peptide (B... View More
Product Details
ACS-001-50UL
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
(C)SGQLDAAGFQKIYK, corresponding to amino acid residues 40-53 of rat NCS1, Intracellular
Conjugate
Form
Lyophilized
Concentration
0.85 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 1% BSA
Contains
0.05% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Reconstitution: 25 µL, 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C, protected from the light, for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 X g 5 min).
Target Information
This gene is a member of the neuronal calcium sensor gene family, which encode calcium-binding proteins expressed predominantly in neurons. The protein encoded by this gene regulates G protein-coupled receptor phosphorylation in a calcium-dependent manner and can substitute for calmodulin. The protein is associated with secretory granules and modulates synaptic transmission and synaptic plasticity. Multiple transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: frequenin; Frequenin homolog; Frequenin-like protein; Frequenin-like ubiquitous protein; NCS-1; Neuronal calcium sensor 1; neuronal calcium sensor-1
Gene Aliases: 9430075O15Rik; A730032G13Rik; AI836659; FLUP; FREQ; Mfreq; NCS-1; NCS1
UniProt ID: (Human) P62166, (Mouse) Q8BNY6, (Rat) P62168
Entrez Gene ID: (Human) 23413, (Mouse) 14299, (Rat) 65153
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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