This gene encodes a thiol-activated peptidase that is phosphorylated in M phase of the cell cycle. Phosphorylation regulates the cell cycle-dependent distribution of this protein, with a fraction of the protein bound strongly to centrosomes in interphase and localized to mitotic spindles in early M phase. Overall, this protein plays a role in nervous system development. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
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Protein Aliases: DKFZp451M0318; endooligopeptidase A; LIS1-interacting protein NUDEL; LIS1-interacting protein NUDEL; endooligopeptidase A; Mitosin-associated protein 1; mitosin-associated protein MITAP1; mNudE-L; nuclear disribution gene E like; nuclear distribution gene E-like homolog 1; Nuclear distribution protein nudE-like 1; nudE neurodevelopment protein 1-like 1; nudE nuclear distribution E homolog-like 1; nudE nuclear distribution gene E homolog like 1; nudE nuclear distribution gene E homolog-like 1; NUDE-like protein; Protein mNudE-like; Protein Nudel
Gene Aliases: 2600006O07Rik; EOPA; MITAP1; mNudel; NDE1L1; NDE2; NDEL1; NUDE2; NUDEL