Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Product Details
CF503353
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Mouse
/ IgG2a
Class
Monoclonal
Type
Antibody
Clone
OTI5E11
Immunogen
Full length human recombinant protein of human NDEL1 produced in HEk293 cell.
Conjugate
Form
lyophilized
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.3, with 8% trehalose
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
For reconstitution, we recommend adding 100 µL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiments, we strongly recommend performing another round of desalting. (Zeba Spin Desalting Columns, 7KMWCO, 0.5 mL, Product # 89882)
Target Information
This gene encodes a thiol-activated peptidase that is phosphorylated in M phase of the cell cycle. Phosphorylation regulates the cell cycle-dependent distribution of this protein, with a fraction of the protein bound strongly to centrosomes in interphase and localized to mitotic spindles in early M phase. Overall, this protein plays a role in nervous system development. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: DKFZp451M0318; endooligopeptidase A; Mitosin-associated protein 1; mitosin-associated protein MITAP1; mNudE-L; nuclear disribution gene E like; Nuclear distribution protein nudE-like 1; nudE neurodevelopment protein 1-like 1; nudE nuclear distribution E homolog-like 1; nudE nuclear distribution gene E homolog-like 1; NUDE-like protein; Protein mNudE-like; Protein Nudel
Gene Aliases: 2600006O07Rik; EOPA; MITAP1; mNudel; NDE1L1; NDE2; NDEL1; NUDEL
UniProt ID: (Human) Q9GZM8, (Mouse) Q9ERR1
Entrez Gene ID: (Human) 81565, (Mouse) 83431
establishment of mitotic spindle orientation
neuron migration
inner cell mass cell proliferation
proteolysis
microtubule nucleation
chromosome segregation
sister chromatid cohesion
mitotic centrosome separation
retrograde axonal transport
regulation of neuron projection development
cell migration
cerebral cortex radially oriented cell migration
central nervous system neuron axonogenesis
regulation of intracellular protein transport
positive regulation of GTPase activity
positive regulation of axon extension
vesicle transport along microtubule
positive regulation of axon regeneration
nuclear envelope disassembly
establishment of chromosome localization
centrosome localization
neurofilament cytoskeleton organization
activation of GTPase activity
neuron projection extension
regulation of microtubule motor activity
microtubule cytoskeleton organization
transport
multicellular organism development
nervous system development
cell differentiation
neuron projection development
canonical Wnt signaling pathway
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support