Sequence of this protein is as follows: MAELQEVQIT EEKPLLPGQT PEAAKEAELA ARILLDQGQT HSVETPYVSV TFTVYGTPKP KRPAILTYHD VGLNYKSCFQ PLFQFEDMQE IIQNFVRVHV DAPGMEEGAP VFPLGYQYPS LDQLADMIPC VLQYLNFSTI IGVGVGAGAY ILARYALNHP DTVEGLVLIN IDPNAKGWMD WAAHKLTGLT SSIPEMILGH LFSQEELSGN SELIQKYRNI ITHAPNLDNI ELYWNSYNNR RDLNFERGGD ITLRCPVMLV VECNSKLDPT QTSFLKMADS GGQPQLTQPG KLTEAFKYFL QGMGYMASSC MTRLSRSRTA SLTSAASVDG NRSRSRTLSQ SSESGTLSSG PPGHTMEVSC
NDRG2's gene is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. NDRG2 is a cytoplasmic protein that may play a role in neurite outgrowth. Its gene may be involved in glioblastoma carcinogenesis.This gene is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. The protein encoded by this gene is a cytoplasmic protein that may play a role in neurite outgrowth. This gene may be involved in glioblastoma carcinogenesis. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.
Protein Aliases: cytoplasmic protein Ndr1; DKFZp781G1938; FLJ25522; N-myc downstream regulator 2; N-myc downstream-regulated gene 2 protein; NDR1-related protein NDR2; NDRG2var; Protein NDRG2; Protein Syld709613; syld709613 protein
Gene Aliases: KIAA1248; NDRG2; SYLD
UniProt ID: (Human) Q9UN36
Entrez Gene ID: (Human) 57447
Molecular Function: serine protease